Abstract Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a
developmental encephalopathy caused by pathogenic variants in the gene CDKL5. This …

The X‐linked gene cyclin‐dependent kinase‐like 5 (CDKL5) encodes a serine/threonine
kinase abundantly expressed in the brain. Mutations in CDKL5 have been associated with …

CDKL5 deficiency disorder (CDD) is an X-linked brain disorder of young children and is
caused by pathogenic variants in the cyclin-dependent kinase-like 5 (CDKL5) gene …

This study aims to determine the effect of exercise on the cardiac function, metabolic profiles
and related molecular mechanisms in mice with ischemic-induced heart failure (HF). HF was …

Cyclin-dependent kinase-like 5 (CDKL5) deficiency is a neurodevelopmental disorder
characterized by epileptic seizures, severe intellectual disability, and autistic features. Mice …

CDKL5 deficiency disorder (CDD), a rare and severe neurodevelopmental disease caused
by mutations in the X-linked CDKL 5 gene, is characterized by early-onset epilepsy …

Loss‐of‐function mutations in CDKL 5 kinase cause severe neurodevelopmental delay and
early‐onset seizures. Identification of CDKL 5 substrates is key to understanding its function …

Background Maternal diet plays a beneficial role in the health, including the
neurodevelopment, of offspring. Insufficient fibre consumption among the general population …

Background CDKL5 deficiency disorder (CDD), a severe neurodevelopmental disorder
characterized by early onset epilepsy, intellectual disability, and autistic features, is caused …

Mutations in the Cyclin-dependent kinase-like 5 (CDKL5) gene cause severe
neurodevelopmental disorders. Recently we have generated Cdkl5 KO mice by targeting …