[HTML][HTML] Network propagation: a universal amplifier of genetic associations
Biological networks are powerful resources for the discovery of genes and genetic modules
that drive disease. Fundamental to network analysis is the concept that genes underlying the …
that drive disease. Fundamental to network analysis is the concept that genes underlying the …
[HTML][HTML] A travel guide to Cytoscape plugins
Cytoscape is open-source software for integration, visualization and analysis of biological
networks. It can be extended through Cytoscape plugins, enabling a broad community of …
networks. It can be extended through Cytoscape plugins, enabling a broad community of …
GeneMANIA update 2018
M Franz, H Rodriguez, C Lopes, K Zuberi… - Nucleic acids …, 2018 - academic.oup.com
Abstract GeneMANIA (http://genemania. org) is a flexible user-friendly web site for
generating hypotheses about gene function, analyzing gene lists and prioritizing genes for …
generating hypotheses about gene function, analyzing gene lists and prioritizing genes for …
QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
Summary N 7-methylguanosine (m 7 G) modification, routinely occurring at mRNA 5′ cap
or within tRNAs/rRNAs, also exists internally in messenger RNAs (mRNAs). Although m 7 G …
or within tRNAs/rRNAs, also exists internally in messenger RNAs (mRNAs). Although m 7 G …
Lineage-specific genome architecture links enhancers and non-coding disease variants to target gene promoters
BM Javierre, OS Burren, SP Wilder, R Kreuzhuber… - Cell, 2016 - cell.com
Long-range interactions between regulatory elements and gene promoters play key roles in
transcriptional regulation. The vast majority of interactions are uncharted, constituting a …
transcriptional regulation. The vast majority of interactions are uncharted, constituting a …
Biological network exploration with Cytoscape 3
Cytoscape is one of the most popular open‐source software tools for the visual exploration
of biomedical networks composed of protein, gene, and other types of interactions. It offers …
of biomedical networks composed of protein, gene, and other types of interactions. It offers …
Inhibition of the mitochondrial protease ClpP as a therapeutic strategy for human acute myeloid leukemia
A Cole, Z Wang, E Coyaud, V Voisin, M Gronda… - Cancer cell, 2015 - cell.com
From an shRNA screen, we identified ClpP as a member of the mitochondrial proteome
whose knockdown reduced the viability of K562 leukemic cells. Expression of this …
whose knockdown reduced the viability of K562 leukemic cells. Expression of this …
CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data
G Bindea, J Galon, B Mlecnik - Bioinformatics, 2013 - academic.oup.com
The CluePedia Cytoscape plugin is a search tool for new markers potentially associated to
pathways. CluePedia calculates linear and non-linear statistical dependencies from …
pathways. CluePedia calculates linear and non-linear statistical dependencies from …
[HTML][HTML] TCGA Workflow: Analyze cancer genomics and epigenomics data using Bioconductor packages
Biotechnological advances in sequencing have led to an explosion of publicly available
data via large international consortia such as The Cancer Genome Atlas (TCGA), The …
data via large international consortia such as The Cancer Genome Atlas (TCGA), The …
GeneMANIA prediction server 2013 update
K Zuberi, M Franz, H Rodriguez, J Montojo… - Nucleic acids …, 2013 - academic.oup.com
Abstract GeneMANIA (http://www. genemania. org) is a flexible user-friendly web interface
for generating hypotheses about gene function, analyzing gene lists and prioritizing genes …
for generating hypotheses about gene function, analyzing gene lists and prioritizing genes …