► Detailed survey of experimental and modeling approaches to cellular rhythms.► Cellular
rhythms in development: from cAMP oscillations to the segmentation clock.► Frequency …

The interactions between mathematics and physiology have a long and illustrious history, of
which the study of calcium signalling is but a small chapter. Nevertheless, for those involved …

Oscillations in the concentration of free cytosolic Ca2+ are an important and ubiquitous
control mechanism in many cell types. It is thus correspondingly important to understand the …

A central component of receptor-evoked Ca2+ signaling is store-operated Ca2+ entry
(SOCE), which is activated by the assembly of STIM1-Orai1 channels in endoplasmic …

Salivary fluid secretion involves an intricate choreography of membrane transporters to
result in the trans-epithelial movement of NaCl and water into the acinus lumen. Current …

Calcium (Ca2+) is a key signaling ion that plays a fundamental role in many cellular
processes in most types of tissues and organisms. The versatility of this signaling pathway is …

Inspired by biological systems, molecular communication has been proposed as a new
communication paradigm that uses biochemical signals to transfer information from one …

We review a multiscale model of saliva secretion, describing in brief how the model is
constructed and what we have so far learned from it. The model begins at the level of inositol …

Saliva is secreted from the acinar cells of the salivary glands, using mechanisms that are
similar to other types of water-transporting epithelial cells. Using a combination of theoretical …

The cytosolic concentration of free calcium ions ([Ca 2+]) is an important intracellular
messenger in most cell types, and the spatial distribution of [Ca 2+] is often critical. In a …