Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

SN Amrun, CYP Lee, B Lee, SW Fong, BE Young… - …, 2020 - thelancet.com
Background Given the unceasing worldwide surge in COVID-19 cases, there is an
imperative need to develop highly specific and sensitive serology assays to define exposure …

Linear and Continuous Flavivirus Epitopes From Naturally Infected Humans

MJ Fumagalli, LTM Figueiredo… - Frontiers in Cellular and …, 2021 - frontiersin.org
This manuscript is an up-to-date review of experimentally validated linear and continuous
epitopes identified from arbovirus members of the Flavivirus genus. We summarized 153 …

[HTML][HTML] Structural Biology of Flavivirus NS1 Protein and Its Antibody Complexes

BLA Chew, Q Pan, H Hu, D Luo - Antiviral Research, 2024 - Elsevier
The genus of flavivirus includes many mosquito-borne human pathogens, such as Zika
(ZIKV) and the four serotypes of dengue (DENV1-4) viruses, that affect billions of people as …

The Epidermal Growth Factor Receptor Is a Relevant Host Factor in the Early Stages of The Zika Virus Life Cycle In Vitro

C Sabino, D Bender, ML Herrlein, E Hildt - Journal of virology, 2021 - Am Soc Microbiol
Zika virus (ZIKV) is a flavivirus that is well known for the epidemic in the Americas in 2015
and 2016 in which microcephaly in newborns and other neurological complications were …

A potent fluorescent biosensor integrating 3D DNA walker with localized catalytic hairpin assembly for highly sensitive and enzyme-free Zika virus detection

GX Liang, SY Ye, HM Yu, KR Zhao, PF Liu… - Sensors and Actuators B …, 2022 - Elsevier
Zika virus (ZIKV) with worldwide distribution, high incidence and great harm, has emerged
as a serious global health threat in the past few years. There is an urgent need for fast, low …

Linear epitope mapping in the E and NS1 proteins of dengue and Zika viruses: Prospection of peptides for vaccines and diagnostics

VH Aquino, MJ Fumagalli, A Silva… - Plos one, 2023 - journals.plos.org
The arrival of the Zika virus (ZIKV) in dengue virus (DENV)-endemic areas has posed
challenges for both differential diagnosis and vaccine development. Peptides have shown …

[HTML][HTML] NS1: A promising novel target antigen with strong immunogenicity and protective efficacy for avian flavivirus vaccine development

J Huang, W Wang, T Yu, M Wang, M Liu, D Zhu… - Poultry Science, 2024 - Elsevier
Tembusu virus (TMUV), an avian pathogenic flavivirus, has emerged as a significant threat
to the duck industry in Southeast Asia, causing substantial economic losses. Due to the …

Novel differential linear B‐cell epitopes to identify Zika and dengue virus infections in patients

SN Amrun, WX Yee, F Abu Bakar, B Lee… - Clinical & …, 2019 - Wiley Online Library
Abstract Objectives Recent Zika virus (ZIKV) outbreaks challenged existing laboratory
diagnostic standards, especially for serology‐based methods. Because of the genetic and …

Design, development, and validation of multi-epitope proteins for serological diagnosis of Zika virus infections and discrimination from dengue virus seropositivity

SH Pereira, M Sá Magalhães Serafim… - PLOS Neglected …, 2024 - journals.plos.org
Zika virus (ZIKV), an arbovirus from the Flaviviridae family, is the causative agent of Zika
fever, a mild and frequent oligosymptomatic disease in humans. Nonetheless, on rare …

Modulation of cellular machineries by Zika virus‐encoded proteins

S Dong, MZX Xiao, Q Liang - Journal of Medical Virology, 2023 - Wiley Online Library
The strain of Zika virus (ZIKV) that circulated during the 2015 epidemic in Brazil has been
associated with more than 2000 cases of microcephaly from September 2015 through …