CCN2 (Cellular Communication Network factor 2) in the bone marrow microenvironment, normal and malignant hematopoiesis
RJ Leguit, RAP Raymakers, KM Hebeda… - Journal of cell …, 2021 - Springer
CCN2, formerly termed Connective Tissue Growth Factor, is a protein belonging to the
Cellular Communication Network (CCN)-family of secreted extracellular matrix-associated …
Cellular Communication Network (CCN)-family of secreted extracellular matrix-associated …
Proteasome inhibitors interrupt the activation of Non-Canonical NF-κB signaling pathway and induce cell apoptosis in Cytarabine-Resistant HL60 cells
Over half of older patients with acute myeloid leukemia (AML) do not respond to cytotoxic
chemotherapy, and most responders relapse because of drug resistance. Cytarabine is the …
chemotherapy, and most responders relapse because of drug resistance. Cytarabine is the …
NR4A1 knockdown confers hepatoprotection against ischaemia‐reperfusion injury by suppressing TGFβ1 via inhibition of CYR61/NF‐κB in mouse hepatocytes
J Cao, T Xu, C Zhou, S Wang, B Jiang… - Journal of Cellular …, 2021 - Wiley Online Library
Nuclear receptor subfamily 4, group A, member 1 (NR4A1) can aggravate ischaemia‐
reperfusion (I/R) injury in the heart, kidney and brain. Thus, the present study aimed to …
reperfusion (I/R) injury in the heart, kidney and brain. Thus, the present study aimed to …
Chemotherapy-initiated cysteine-rich protein 61 decreases acute B-lymphoblastic leukemia chemosensitivity
P Shi, Z Lin, Y Song, Z Li, M Zeng, L Luo, Y Cao… - Journal of Cancer …, 2024 - Springer
Purpose Chemoresistance is a major challenge for acute lymphoblastic leukemia (ALL)
treatment. Cysteine-rich protein 61 (Cyr61) plays an important role in drug resistance …
treatment. Cysteine-rich protein 61 (Cyr61) plays an important role in drug resistance …
GNL3L exhibits pro-tumor activities via NF-κB pathway as a poor prognostic factor in acute myeloid leukemia
J Li, Z Wu, Y Pan, Y Chen, J Chu, Y Cong, Q Fang - Journal of Cancer, 2024 - jcancer.org
Acute myeloid leukemia (AML) is the leukemia with the worst prognosis, and current
knowledge of AML pathogenesis and available therapies for AML remain limited. 40% of …
knowledge of AML pathogenesis and available therapies for AML remain limited. 40% of …
Paeoniflorin sensitizes imatinib mesylate-resistant chronic myeloid leukemia cells via the inhibition of Cyr61 production
Y Song, L Luo, Z Lin, T Zhang, Z Li, Y Cao… - Anti-Cancer …, 2025 - journals.lww.com
Imatinib mesylate (IM) is a first-line therapy for chronic myeloid leukemia (CML) and exhibits
good therapeutic effects, but not in all patients with CML owing to drug resistance. Our …
good therapeutic effects, but not in all patients with CML owing to drug resistance. Our …
[HTML][HTML] Cyr61 mediates oxaliplatin resistance in colorectal cancer cells by regulating Bcl-xL expression
Y Song, Y Kang, Z Lin, M Zeng, P Shi, J Lin, P Lu… - Journal of …, 2021 - ncbi.nlm.nih.gov
Although the clinical application of oxaliplatin (L-OHP) has improved the survival of
colorectal cancer (CRC) patients, approximately half of patients with CRC fail to achieve …
colorectal cancer (CRC) patients, approximately half of patients with CRC fail to achieve …
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)
F Nikravesh, H Arezoomand, M Nooshadokht… - BioImpacts, 2024 - bi.tbzmed.ac.ir
Introduction: The current understanding highlights the intricate relationship between
leukemic cells and their microenvironment, emphasizing the significant impact of …
leukemic cells and their microenvironment, emphasizing the significant impact of …
Evaluación del efecto quimiorresistente de la sobreexpresión del gen asociado a mal pronóstico IGJ en un modelo de leucemia linfoblástica aguda de precursores B
CE Moreno Cristancho - repositorio.unal.edu.co
Acute Lymphoblastic Leukemia (ALL) is a hematologic neoplasm characterized by the
disordered proliferation of progenitor cells of B or T lymphoid lineage, commonly diagnosed …
disordered proliferation of progenitor cells of B or T lymphoid lineage, commonly diagnosed …
[PDF][PDF] Daunorubicin induces Cysteine‐rich protein 61 to decreases the Chemosensitivity through the ATM/NF-κB pathway in B-acute lymphoblastic leukemia
P Shi, Z Lin, Y Song, Z Li, M Zeng, L Luo, Y Cao, X Zhu - 2022 - scholar.archive.org
Background: Acute lymphoblastic leukemia ALL is the second most common hematologic
malignancy worldwide with B-acute lymphoblastic leukemia B-ALL accounting for 70%-80 …
malignancy worldwide with B-acute lymphoblastic leukemia B-ALL accounting for 70%-80 …