Computational models for lncRNA function prediction and functional similarity calculation

X Chen, YZ Sun, NN Guan, J Qu… - Briefings in …, 2019 - academic.oup.com
From transcriptional noise to dark matter of biology, the rapidly changing view of long non-
coding RNA (lncRNA) leads to deep understanding of human complex diseases induced by …

Data integration and predictive modeling methods for multi-omics datasets

M Kim, I Tagkopoulos - Molecular omics, 2018 - pubs.rsc.org
Translating data to knowledge and actionable insights is the Holy Grail for many scientific
fields, including biology. The unprecedented massive and heterogeneous data have created …

PBMDA: A novel and effective path-based computational model for miRNA-disease association prediction

ZH You, ZA Huang, Z Zhu, GY Yan, ZW Li… - PLoS computational …, 2017 - journals.plos.org
In the recent few years, an increasing number of studies have shown that microRNAs
(miRNAs) play critical roles in many fundamental and important biological processes. As …

A novel approach based on KATZ measure to predict associations of human microbiota with non-infectious diseases

X Chen, YA Huang, ZH You, GY Yan, XS Wang - Bioinformatics, 2017 - academic.oup.com
Motivation Accumulating clinical observations have indicated that microbes living in the
human body are closely associated with a wide range of human noninfectious diseases …

[HTML][HTML] HGIMDA: Heterogeneous graph inference for miRNA-disease association prediction

X Chen, CC Yan, X Zhang, ZH You, YA Huang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recently, microRNAs (miRNAs) have drawn more and more attentions because
accumulating experimental studies have indicated miRNA could play critical roles in multiple …

[HTML][HTML] MCMDA: Matrix completion for MiRNA-disease association prediction

JQ Li, ZH Rong, X Chen, GY Yan, ZH You - Oncotarget, 2017 - ncbi.nlm.nih.gov
Nowadays, researchers have realized that microRNAs (miRNAs) are playing a significant
role in many important biological processes and they are closely connected with various …

[HTML][HTML] IRWRLDA: improved random walk with restart for lncRNA-disease association prediction

X Chen, ZH You, GY Yan, DW Gong - Oncotarget, 2016 - ncbi.nlm.nih.gov
In recent years, accumulating evidences have shown that the dysregulations of lncRNAs are
associated with a wide range of human diseases. It is necessary and feasible to analyze …

LSTM-PHV: prediction of human-virus protein–protein interactions by LSTM with word2vec

S Tsukiyama, MM Hasan, S Fujii… - Briefings in …, 2021 - academic.oup.com
Viral infection involves a large number of protein–protein interactions (PPIs) between human
and virus. The PPIs range from the initial binding of viral coat proteins to host membrane …

RKNNMDA: ranking-based KNN for MiRNA-disease association prediction

X Chen, QF Wu, GY Yan - RNA biology, 2017 - Taylor & Francis
Cumulative verified experimental studies have demonstrated that microRNAs (miRNAs)
could be closely related with the development and progression of human complex diseases …

Prediction of protein–protein interaction using graph neural networks

K Jha, S Saha, H Singh - Scientific Reports, 2022 - nature.com
Proteins are the essential biological macromolecules required to perform nearly all
biological processes, and cellular functions. Proteins rarely carry out their tasks in isolation …