Reprogramming of plant central metabolism in response to abiotic stresses: A metabolomics view
Y Xu, X Fu - International Journal of Molecular Sciences, 2022 - mdpi.com
Abiotic stresses rewire plant central metabolism to maintain metabolic and energy
homeostasis. Metabolites involved in the plant central metabolic network serve as a hub for …
homeostasis. Metabolites involved in the plant central metabolic network serve as a hub for …
Quality assurance procedures for mass spectrometry untargeted metabolomics. a review
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …
capabilities for the investigation of health and disease, as well as the wide applicability for …
The gut metabolite indole-3 propionate promotes nerve regeneration and repair
E Serger, L Luengo-Gutierrez, JS Chadwick, G Kong… - Nature, 2022 - nature.com
The regenerative potential of mammalian peripheral nervous system neurons after injury is
critically limited by their slow axonal regenerative rate. Regenerative ability is influenced by …
critically limited by their slow axonal regenerative rate. Regenerative ability is influenced by …
[HTML][HTML] Tau PTM profiles identify patient heterogeneity and stages of Alzheimer's disease
To elucidate the role of Tau isoforms and post-translational modification (PTM) stoichiometry
in Alzheimer's disease (AD), we generated a high-resolution quantitative proteomics map of …
in Alzheimer's disease (AD), we generated a high-resolution quantitative proteomics map of …
mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions
P Kaplonek, D Cizmeci, S Fischinger… - Science translational …, 2022 - science.org
The successful development of several coronavirus disease 2019 (COVID-19) vaccines has
substantially reduced morbidity and mortality in regions of the world where the vaccines …
substantially reduced morbidity and mortality in regions of the world where the vaccines …
Metformin enhances autophagy and normalizes mitochondrial function to alleviate aging-associated inflammation
Age is a non-modifiable risk factor for the inflammation that underlies age-associated
diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine …
diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine …
MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
We present a new update to MetaboAnalyst (version 4.0) for comprehensive metabolomic
data analysis, interpretation, and integration with other omics data. Since the last major …
data analysis, interpretation, and integration with other omics data. Since the last major …
[HTML][HTML] PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
The efficacy of immunotherapy is limited by the paucity of T cells delivered and infiltrated into
the tumors through aberrant tumor vasculature. Here, we report that phosphoglycerate …
the tumors through aberrant tumor vasculature. Here, we report that phosphoglycerate …
Human metabolome variation along the upper intestinal tract
Most processing of the human diet occurs in the small intestine. Metabolites in the small
intestine originate from host secretions, plus the ingested exposome and microbial …
intestine originate from host secretions, plus the ingested exposome and microbial …
Metabolomics of exhaled breath in critically ill COVID-19 patients: A pilot study
S Grassin-Delyle, C Roquencourt, P Moine, G Saffroy… - …, 2021 - thelancet.com
Background Early diagnosis of coronavirus disease 2019 (COVID-19) is of the utmost
importance but remains challenging. The objective of the current study was to characterize …
importance but remains challenging. The objective of the current study was to characterize …