Acute pancreatitis is an acute inflammatory process of the pancreas that frequently involves
peripancreatic tissues and at times remote organ systems. The severity of the disease varies …

The incidence of acute pancreatitis (AP) is increasing globally and mortality could be high
among patients with organ failure and infected necrosis. The predominant factors …

Oral delivery of small interfering RNA (siRNA) provides a promising paradigm for treating
diseases that require regular injections. However, the multiple gastrointestinal (GI) and …

Background Acute pancreatitis has long been considered a disorder of pancreatic self-
digestion, in which intracellular activation of digestive proteases induces tissue injury …

This review addresses oxidative stress and redox signaling in the pancreas under healthy
physiological conditions as well as in acute pancreatitis, chronic pancreatitis, pancreatic …

Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may
lead to a severe systemic inflammatory response. A key event in pancreatic damage is the …

Background Protein tyrosine phosphatase 1B (PTP1B) is a member of the non-
transmembrane phosphotyrosine phosphatase family. Recently, PTP1B has been proposed …

Ca 2+ is a universal intracellular messenger that controls a wide range of cellular processes.
In pancreatic acinar cells, acetylcholine and cholecystokinin regulate secretion via …

Acute pancreatitis is an acute inflammatory process localized in the pancreatic gland that
frequently involves peripancreatic tissues. It is still under investigation why an episode of …

Purpose: To determine if a high-fat diet (HFD) induces meibomian gland (MG) inflammation
in mice. Methods: Male C57BL/6J mice were fed a standard diet (SD), HFD, or HFD …