Selenocysteine in proteins—properties and biotechnological use
L Johansson, G Gafvelin, ESJ Arnér - Biochimica et Biophysica Acta (BBA) …, 2005 - Elsevier
Selenocysteine (Sec), the 21st amino acid, exists naturally in all kingdoms of life as the
defining entity of selenoproteins. Sec is a cysteine (Cys) residue analogue with a selenium …
defining entity of selenoproteins. Sec is a cysteine (Cys) residue analogue with a selenium …
Artificial selenoenzymes: designed and redesigned
X Huang, X Liu, Q Luo, J Liu, J Shen - Chemical Society Reviews, 2011 - pubs.rsc.org
Enzymes, highly evolved machinery developed by nature, catalyse reactions with formidable
efficiency and specificity under mild conditions. Considerable efforts have been devoted for …
efficiency and specificity under mild conditions. Considerable efforts have been devoted for …
Aminoacyl-tRNAs: setting the limits of the genetic code
Aminoacyl-tRNAs (aa-tRNAs) are simple molecules with a single purpose—to serve as
substrates for translation. They consist of mature tRNAs to which an amino acid has been …
substrates for translation. They consist of mature tRNAs to which an amino acid has been …
Proteogenomics: needs and roles to be filled by proteomics in genome annotation
C Ansong, SO Purvine, JN Adkins… - Briefings in …, 2008 - academic.oup.com
While genome sequencing efforts reveal the basic building blocks of life, a genome
sequence alone is insufficient for elucidating biological function. Genome annotation—the …
sequence alone is insufficient for elucidating biological function. Genome annotation—the …
Paired termini stabilize antisense RNAs and enhance conditional gene silencing in Escherichia coli
Reliable methods for conditional gene silencing in bacteria have been elusive. To improve
silencing by expressed antisense RNAs (asRNAs), we systematically altered several design …
silencing by expressed antisense RNAs (asRNAs), we systematically altered several design …
Selenocysteine insertion at a predefined UAG codon in a release factor 1 (RF1)-depleted Escherichia coli host strain bypasses species barriers in recombinant …
Q Cheng, ESJ Arnér - Journal of biological chemistry, 2017 - ASBMB
Selenoproteins contain the amino acid selenocysteine (Sec), co-translationally inserted at a
predefined UGA opal codon by means of Sec-specific translation machineries. In …
predefined UGA opal codon by means of Sec-specific translation machineries. In …
An algorithm for identification of bacterial selenocysteine insertion sequence elements and selenoprotein genes
Y Zhang, VN Gladyshev - Bioinformatics, 2005 - academic.oup.com
Abstract Motivation: Incorporation of selenocysteine (Sec) into proteins in response to UGA
codons requires a cis-acting RNA structure, Sec insertion sequence (SECIS) element …
codons requires a cis-acting RNA structure, Sec insertion sequence (SECIS) element …
The microbial selenoproteome of the Sargasso Sea
Y Zhang, DE Fomenko, VN Gladyshev - Genome biology, 2005 - Springer
Abstract Background Selenocysteine (Sec) is a rare amino acid which occurs in proteins in
major domains of life. It is encoded by TGA, which also serves as the signal for termination of …
major domains of life. It is encoded by TGA, which also serves as the signal for termination of …
Pseudouridines in RNAs: switching atoms means shifting paradigms
The structure, stability, and function of various coding and noncoding RNAs are influenced
by chemical modifications. Pseudouridine (Ψ) is one of the most abundant post …
by chemical modifications. Pseudouridine (Ψ) is one of the most abundant post …
The many levels of control on bacterial selenoprotein synthesis
S Yoshizawa, A Böck - Biochimica et Biophysica Acta (BBA)-General …, 2009 - Elsevier
Selenium shares many chemical facets with sulphur but differs from it in the redox potential,
especially of the Se2−/S2− oxidation state. The higher chemical reactivity of the …
especially of the Se2−/S2− oxidation state. The higher chemical reactivity of the …