Gut microbiota-derived metabolites in irritable bowel syndrome

L Xiao, Q Liu, M Luo, L Xiong - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Irritable bowel syndrome (IBS) is the most common functional bowel disorder worldwide and
is associated with visceral hypersensitivity, gut motility, immunomodulation, gut microbiota …

Neurotransmitter dysfunction in irritable bowel syndrome: emerging approaches for management

M Gros, B Gros, JE Mesonero, E Latorre - Journal of clinical medicine, 2021 - mdpi.com
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder whose aetiology is
still unknown. Most hypotheses point out the gut-brain axis as a key factor for IBS. The axis is …

Neurotransmitter and intestinal interactions: focus on the microbiota-gut-brain axis in irritable bowel syndrome

M Chen, G Ruan, L Chen, S Ying, G Li, F Xu… - Frontiers in …, 2022 - frontiersin.org
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder of unknown etiology.
IBS is caused by a disruption in the gut-brain axis. Given the importance of the gut …

Molecular mechanisms of microbiota-mediated pathology in irritable bowel syndrome

Y Mishima, S Ishihara - International journal of molecular sciences, 2020 - mdpi.com
Irritable bowel syndrome (IBS) is one of the most prevalent functional gastrointestinal
disorders, and accumulating evidence gained in both preclinical and clinical studies indicate …

GABA-producing Lactobacillus plantarum inhibits metastatic properties and induces apoptosis of 5-FU-resistant colorectal cancer cells via GABAB receptor signaling

JJ An, H Seok, EM Ha - Journal of Microbiology, 2021 - Springer
Fluorouracil (5-FU) is an essential drug in systemic chemotherapy treatments for colorectal
cancer (CRC). Despite the development of several treatment strategies over the past …

Anti-Helicobacter pylori activity of potential probiotic Lactiplantibacillus pentosus SLC13

TTD Thuy, PY Kuo, SM Lin, CY Kao - BMC microbiology, 2022 - Springer
Background Here, we aimed to evaluate and compare the anti-Helicobacter pylori activity of
potential probiotic Lactiplantibacillus pentosus SLC13 to Lactobacillus gasseri BCRC 14619 …

From bugs to brain: unravelling the GABA signalling networks in the brain-gut-microbiome axis

D Belelli, JJ Lambert, MLY Wan, AR Monteiro, DJ Nutt… - Brain, 2024 - academic.oup.com
Convergent data, across species, paint a compelling picture of the critical role of the gut and
its resident microbiota in several brain functions and disorders. The chemicals mediating …

Supplementation with Lactobacillus helveticus NS8 alleviated behavioral, neural, endocrine, and microbiota abnormalities in an endogenous rat model of depression

H Alatan, S Liang, Y Shimodaira, X Wu, X Hu… - Frontiers in …, 2024 - frontiersin.org
Introduction Major depressive disorder is a condition involving microbiota–gut–brain axis
dysfunction. Increasing research aims to improve depression through gut microbiota …

Gut feelings: the microbiota-gut-brain axis on steroids

SY So, TC Savidge - American Journal of Physiology …, 2022 - journals.physiology.org
The intricate connection between central and enteric nervous systems is well established
with emerging evidence linking gut microbiota function as a significant new contributor to gut …

[HTML][HTML] Activation of GABABR Attenuates Intestinal Inflammation by Reducing Oxidative Stress through Modulating the TLR4/MyD88/NLRP3 Pathway and Gut …

Z Deng, D Li, L Wang, J Lan, J Wang, Y Ma - Antioxidants, 2024 - mdpi.com
Oxidative stress emerges as a prominent factor in the onset and progression of intestinal
inflammation, primarily due to its critical role in damaging cells and tissues. GABAergic …