Animal models for COVID-19

C Muñoz-Fontela, WE Dowling, SGP Funnell, PS Gsell… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …

Next generation sequencing of SARS-CoV-2 genomes: challenges, applications and opportunities

M Chiara, AM D'Erchia, C Gissi… - Briefings in …, 2021 - academic.oup.com
Various next generation sequencing (NGS) based strategies have been successfully used in
the recent past for tracing origins and understanding the evolution of infectious agents …

COVID-19 CG enables SARS-CoV-2 mutation and lineage tracking by locations and dates of interest

AT Chen, K Altschuler, SH Zhan, YA Chan… - Elife, 2021 - elifesciences.org
COVID-19 CG (covidcg. org) is an open resource for tracking SARS-CoV-2 single-nucleotide
variations (SNVs), lineages, and clades using the virus genomes on the GISAID database …

[HTML][HTML] Use of genomics to track coronavirus disease outbreaks, New Zealand

JL Geoghegan, J Douglas, X Ren… - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
Real-time genomic sequencing has played a major role in tracking the global spread of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), contributing greatly to …

Drug repurposing studies targeting SARS-CoV-2: an ensemble docking approach on drug target 3C-like protease (3CLpro)

S Koulgi, V Jani, M Uppuladinne… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic has been responsible for several deaths worldwide. The causative
agent behind this disease is the Severe Acute Respiratory Syndrome–novel Coronavirus 2 …

Pharmacological Modulators of Autophagy as a Potential Strategy for the Treatment of COVID-19

GJS Pereira, AHFF Leao, AG Erustes… - International journal of …, 2021 - mdpi.com
The family of coronaviruses (CoVs) uses the autophagy machinery of host cells to promote
their growth and replication; thus, this process stands out as a potential target to combat …

Natural plant products as potential inhibitors of RNA dependent RNA polymerase of Severe Acute Respiratory Syndrome Coronavirus-2

S Koulgi, V Jani, M Uppuladinne VN, U Sonavane… - PLoS …, 2021 - journals.plos.org
Drug repurposing studies targeting inhibition of RNA dependent RNA polymerase (RdRP) of
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) have exhibited the …

Web tools to fight pandemics: the COVID-19 experience

D Mercatelli, AN Holding, FM Giorgi - Briefings in bioinformatics, 2021 - academic.oup.com
The current outbreak of COVID-19 has generated an unprecedented scientific response
worldwide, with the generation of vast amounts of publicly available epidemiological …

Perspective on proteomics for virus detection in clinical samples

M Grossegesse, F Hartkopf, A Nitsche… - Journal of Proteome …, 2020 - ACS Publications
One of the most widely used methods to detect an acute viral infection in clinical specimens
is diagnostic real-time polymerase chain reaction. However, because of the COVID-19 …

[HTML][HTML] Animal models of SARS-CoV-2 transmission

RD de Vries, B Rockx, BL Haagmans, S Herfst… - Current Opinion in …, 2021 - Elsevier
Highlights•SARS-CoV-2 is a zoonotic virus that is thought to have emerged from
bats.•Human-to-human transmission of SARS-CoV-2 is the major driver of the …