Abstract The 2022 World Health Organization (WHO) classification of the urinary and male
genital tumors was recently published by the International Agency for Research on Cancer …

Context.—Controversies and uncertainty persist in prostate cancer grading. Objective.—To
update grading recommendations. Data Sources.—Critical review of the literature along with …

The NCCN Guidelines for Prostate Cancer include recommendations regarding diagnosis,
risk stratification and workup, treatment options for localized disease, and management of …

The cancer transcriptome is remarkably complex, including low-abundance transcripts,
many not polyadenylated. To fully characterize the transcriptome of localized prostate …

Background Innovations in treatments, imaging, and molecular characterisation in advanced
prostate cancer have improved outcomes, but various areas of management still lack high …

Prostate cancer is the most frequent nonskin cancer and second most common cause of
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …

Multiple studies have confirmed that speckle-type pox virus and zinc finger (POZ) protein
(SPOP) functions as a substrate adaptor of cullin 3-based E3 ligase and has a crucial role in …

Intraductal carcinoma of the prostate (IDC-P) is a lethal prostate cancer subtype that
generally coexists with invasive high-grade prostate acinar adenocarcinoma (PAC) but …

Background Intraductal (IDC) and cribriform (CRIB) histologies in prostate cancer have been
associated with germline BRCA2 (gBRCA2) mutations in small retrospective series, leading …

Purpose: This multicenter randomized phase 2 trial investigates the impact of intense
androgen deprivation on radical prostatectomy pathologic response and radiographic and …