Alzheimer's disease (AD) is the most common cause of dementia and accounts for 60–70%
of all cases. It affects millions of people worldwide. AD poses a substantial economic burden …

Alzheimer's Disease (AD) represents a complex interplay of neurological pathways and
molecular mechanisms, with significant impacts on patients' lives. This review synthesizes …

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by the
presence of amyloid-β (Aβ) plaques and tau-containing neurofibrillary tangles, leading to …

Acute ischemic stroke (AIS) remains a major cause of mortality and long-term disability
worldwide, driven by complex and multifaceted etiological factors. Metabolic dysregulation …

Peroxisomes are essential organelles that help mitigate the oxidative damage caused by
reactive oxygen species (ROS) through their antioxidant systems. They perform functions …

Gamma-glutamate is an important excitatory neurotransmitter in the central nervous system
(CNS), which plays an important role in transmitting synapses, plasticity, and other brain …

Neurological disorders such as Alzheimer's, Parkinson's, amyotrophic lateral sclerosis, and
schizophrenia are associated with altered neuronal excitability, resulting from dysfunctions …

G protein-coupled receptors (GPCRs) are a class of transmembrane proteins that distribute
in various organs extensively. They can regulate physiological functions such as perception …

Glutamate transporter-1 (GLT-1) dynamics are implicated in excitotoxicity and Alzheimer's
disease (AD) progression. Early stages of AD are often marked by hyperactivity and …

Reactive astrocytes are key players in HIV-associated neurocognitive disorders (HAND),
and different types of reactive astrocytes play opposing roles in the neuropathologic …