With increasing evidence that microbes colonize tumors, synthetic biology tools are being
leveraged to repurpose bacteria as tumor-specific delivery systems. These engineered …

Recent advances in targeted therapy and immunotherapy have once again raised the hope
that a cure might be within reach for many cancer types. Yet, most late-stage cancers are …

Recent advances in cancer therapeutics, such as targeted therapy and immunotherapy,
have raised the hope for cures for many cancer types. However, there are still ongoing …

Conventional cancer chemotherapy is often associated with toxicity issues. Thus, new drug
delivery systems (DDSs) are developed as alternatives owing to their potential to selectively …

Rapid advances in synthetic biology are driving the development of genetically engineered
microbes as therapeutic agents for a multitude of human diseases, including cancer. The …

The recently emerged exceedingly small magnetic iron oxide nanoparticles (ES-MIONs)(< 5
nm) are promising T 1-weighted contrast agents for magnetic resonance imaging (MRI) due …

Recent advancements in cancer biology, microbiology, and bioengineering have spurred
the development of engineered live biotherapeutics for targeted cancer therapy. In …

Bacteria are emerging as living drugs to treat a broad range of disease indications.
However, the inherent advantages of these replicating and immunostimulatory therapies …

Glioblastoma multiforme (GBM) is one of the worst brain tumors arising from glial cells,
causing many deaths annually. Surgery, chemotherapy, radiotherapy and immunotherapy …

Here, we provide a brief overview of the approaches and strategies underlying bacteria-
based cancer immunotherapy (BCiT). We also describe and summarize research in the field …