Tumour-associated macrophages: versatile players in the tumour microenvironment

ZZ Ji, MKK Chan, ASW Chan, KT Leung… - Frontiers in Cell and …, 2023 - frontiersin.org
Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

[HTML][HTML] Opinion: Atmospheric multiphase chemistry–past, present, and future

JPD Abbatt, AR Ravishankara - Atmospheric Chemistry and …, 2023 - acp.copernicus.org
Multiphase chemistry occurs between chemicals in different atmospheric phases, typically
involving gas–solid and gas–liquid interactions. The importance of atmospheric multiphase …

Oxidized and unsaturated: Key organic aerosol traits associated with cellular reactive oxygen species production in the southeastern United States

F Liu, T Joo, JC Ditto, MG Saavedra… - Environmental …, 2023 - ACS Publications
Exposure to ambient fine particulate matter (PM2. 5) is associated with millions of premature
deaths annually. Oxidative stress through overproduction of reactive oxygen species (ROS) …

Daily exposure to environmental volatile organic compounds triggers oxidative damage: evidence from a large-scale survey in China

M Yan, H Zhu, H Luo, T Zhang, H Sun… - … Science & Technology, 2023 - ACS Publications
Volatile organic compounds (VOCs) are ubiquitous environmental pollutants and have been
implicated in adverse health outcomes. In this study, concentrations of 11 VOC metabolites …

Multiphase Kinetic Modeling of Air Pollutant Effects on Protein Modification and Nitrotyrosine Formation in Epithelial Lining Fluid

A Mishra, S Lelieveld, U Pöschl… - … Science & Technology, 2023 - ACS Publications
Exposure to ambient air pollution is a major risk factor for human health. Inhalation of air
pollutants can enhance the formation of reactive species in the epithelial lining fluid (ELF) of …

Influence of aerosol acidity and organic ligands on transition metal solubility and oxidative potential of fine particulate matter in urban environments

P Shahpoury, S Lelieveld, C Johannessen… - Science of the Total …, 2024 - Elsevier
The adverse health effects of air pollution around the world have been associated with the
inhalation of fine particulate matter (PM 2.5). Such outcomes are thought to be related to the …

[HTML][HTML] Deposition of secondary organic aerosol in human lung model: Effect of photochemically aged aerosol on human respiratory system

HJ Oh, Y Chen, H Kim - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Ultrafine particles (UFP) of Secondary Organic Aerosol (SOA) penetrate deep into the
human respiratory system and exert fatal effects on human health. However, there is little …

Endogenous Nitric Oxide Can Enhance Oxidative Stress Caused by Air Pollutants and Explain Higher Susceptibility of Individuals with Inflammatory Disorders

S Lelieveld, J Lelieveld, A Mishra… - Environmental …, 2024 - ACS Publications
Air pollution causes morbidity and excess mortality. In the epithelial lining fluid of the
respiratory tract, air pollutants trigger a chemical reaction sequence that causes the …

Influence of ambient and endogenous H 2 O 2 on reactive oxygen species concentrations and OH radical production in the respiratory tract

E Dovrou, S Lelieveld, A Mishra, U Pöschl… - Environmental …, 2023 - pubs.rsc.org
Air pollution is a major health risk, but the underlying chemical mechanisms are not yet well
understood. Fine particulate matter (PM2. 5) and gaseous pollutants can generate reactive …

Atmospheric aging modifies the redox potential and toxicity of humic-like substances (HULIS) from biomass burning

C Li, D Calderon-Arrieta, M Pardo, D Cai… - Environmental …, 2023 - pubs.rsc.org
This study investigated the redox potential and toxicological changes of wood smoldering
emitted HULIS due to reactions in the atmosphere and in neutral lung fluids. Fresh HULIS …