[HTML][HTML] Cystic Fibrosis: Understanding Cystic Fibrosis Transmembrane Regulator Mutation Classification and Modulator Therapies

S Anwar, JL Peng, KR Zahid, YM Zhou, Q Ali… - Advances in Respiratory …, 2024 - mdpi.com
Highlights What are the main findings? The study identifies and categorizes the six main
classes of CFTR mutations based on their functional effects. The study explores the …

GC–MS analysis, molecular docking, and apoptotic-based cytotoxic effect of Caladium lindenii Madison extracts toward the HeLa cervical cancer cell line

A Kalsoom, A Altaf, M Sarwar, T Maqbool… - Scientific Reports, 2024 - nature.com
Utilizing medicinal plants and other natural resources to prevent different types of human
cancers is the prime focus of attention. Cervical cancer in women ranks as the fourth most …

Silibinins and curcumin as promising ligands against mutant cystic fibrosis transmembrane regulator protein

A Akram, A Sakhawat, MU Ghani, MU Khan, R Rehman… - AMB Express, 2024 - Springer
Abstract Cystic Fibrosis Transmembrane Regulator (CFTR) is a significant protein that is
responsible for the movement of ions across cell membranes. The cystic fibrosis (CF) occur …

Identification of novel natural compounds against CFTR p. Gly628Arg pathogenic variant

MU Khan, A Sakhawat, R Rehman, AH Wali, MU Ghani… - AMB Express, 2024 - Springer
Cystic fibrosis transmembrane conductance regulator (CFTR) protein is an ion channel
found in numerous epithelia and controls the flow of water and salt across the epithelium …