Abstract Background/Aim To define practical use and to specify the ideal method for
monitoring the liver toxicity of MTX in the management of psoriasis. Objective To …

Psoriasis is a chronic, recurrent disease that affects between 1% and 3% of the population.
Patients with moderate to severe disease generally require phototherapy (eg narrowband …

MTX is an immunosuppressant drug that occupies a key place in the management of many
autoimmune and inflammatory skin diseases. Although MTX has been widely prescribed in …

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable
reference for gastroenterologists, hepatologists, family physicians, internists, pathologists …

Objective To evaluate the efficacy, safety and side‐effects of methotrexate (MTX) in
psoriasis. Design A 26‐year retrospective study. Setting Department of Dermatology, Leipzig …

Methotrexate is a synthetic folic acid analogue valued for both its anti‐proliferative and anti‐
inflammatory properties. Considered one of the original immune‐modifying agents, it is used …

Background Patients receiving long‐term methotrexate for psoriasis are at risk of developing
hepatic fibrosis. Repeated liver biopsy has long been regarded as the only reliable method …

Background: Low-dose methotrexate (MTX) has been shown to be effective in the treatment
of systemic sclerosis. Objective: We evaluated the effect of low-dose MTX on widespread …

Clinically, erythema multiforme involves macular, papular or urticarial lesions, as well as the
classical iris or 'target lesions', distributed preferentially on the distal extremities. Lesions …

Despite the current use and ongoing development of the biological therapies
'traditional'systemic agents will continue to form a key part of the therapeutic armamentarium …