Beckwith-Wiedemann syndrome (BWS), a human genomic imprinting disorder, is
characterized by phenotypic variability that might include overgrowth, macroglossia …

Beckwith–Wiedemann syndrome (BWS) is a model disorder for the study of imprinting,
growth dysregulation, and tumorigenesis. Unique observations in this disorder point to an …

Patients with Beckwith–Wiedemann syndrome (BWS) have an increased risk to develop
cancer in childhood, especially Wilms tumor and hepatoblastoma. The risk varies depending …

Beckwith–Wiedemann syndrome (BWS) is an imprinting disorder characterized by
overgrowth, tumor predisposition, and congenital malformations. Approximately 85% of …

Abstract Beckwith–Wiedemann syndrome (BWS), a human genomic imprinting disorder, is
characterized by phenotypic variability that might include overgrowth, macroglossia …

Abstract Our understanding of Beckwith–Wiedemann syndrome (BWS) has recently been
enhanced by advances in its molecular characterization. These advances have further …

Our knowledge about inherited susceptibility to adrenocortical carcinoma (ACC) almost
exclusively stems from experiences with familial cancer susceptibility syndromes, which are …

Numerous multiple malformation syndromes associated with pathologic overgrowth have
been described and, for many, their molecular bases elucidated. This review describes the …

Liver tumors in childhood are rare and are typically not detected clinically until they reach a
large size and often spread within the organ or metastasize. This can make surgical …

An understanding of the role of inherited cancer predisposition syndromes in pediatric tumor
diagnoses continues to develop as more information is learned through the application of …