Advances in predicting subcellular localization of multi-label proteins and its implication for developing multi-target drugs
KC Chou - Current medicinal chemistry, 2019 - ingentaconnect.com
The smallest unit of life is a cell, which contains numerous protein molecules. Most of the
functions critical to the cell's survival are performed by these proteins located in its different …
functions critical to the cell's survival are performed by these proteins located in its different …
A comparison and assessment of computational method for identifying recombination hotspots in Saccharomyces cerevisiae
Meiotic recombination is one of the most important driving forces of biological evolution,
which is initiated by double-strand DNA breaks. Recombination has important roles in …
which is initiated by double-strand DNA breaks. Recombination has important roles in …
Crop prediction based on soil and environmental characteristics using feature selection techniques
Earlier, crop cultivation was undertaken on the basis of farmers' hands-on expertise.
However, climate change has begun to affect crop yields badly. Consequently, farmers are …
However, climate change has begun to affect crop yields badly. Consequently, farmers are …
Progresses in predicting post-translational modification
KC Chou - International Journal of Peptide Research and …, 2020 - Springer
Identification of the sites of post-translational modifications (PTMs) in protein, RNA, and DNA
sequences is currently a very hot topic. This is because the information thus obtained is very …
sequences is currently a very hot topic. This is because the information thus obtained is very …
iPPI-PseAAC (CGR): Identify protein-protein interactions by incorporating chaos game representation into PseAAC
Investigation into the network of protein–protein interactions (PPIs) will provide valuable
insights into the inner workings of cells. Accordingly, it is crucially important to develop an …
insights into the inner workings of cells. Accordingly, it is crucially important to develop an …
[HTML][HTML] iPSW (2L)-PseKNC: A two-layer predictor for identifying promoters and their strength by hybrid features via pseudo K-tuple nucleotide composition
The promoter is a regulatory DNA region about 81–1000 base pairs long, usually located
near the transcription start site (TSS) along upstream of a given gene. By combining a …
near the transcription start site (TSS) along upstream of a given gene. By combining a …
iRSpot-SPI: Deep learning-based recombination spots prediction by incorporating secondary sequence information coupled with physio-chemical properties via …
Meiotic recombination plays an important role in the process of genetic diversity
generation.“Hotspots” are regions that show a higher rate of meiotic recombination, while …
generation.“Hotspots” are regions that show a higher rate of meiotic recombination, while …
Prediction of land suitability for crop cultivation based on soil and environmental characteristics using modified recursive feature elimination technique with various …
Crop cultivation prediction is an integral part of agriculture and is primarily based on factors
such as soil, environmental features like rainfall and temperature, and the quantum of …
such as soil, environmental features like rainfall and temperature, and the quantum of …
[HTML][HTML] pLoc_bal-mHum: predict subcellular localization of human proteins by PseAAC and quasi-balancing training dataset
KC Chou, X Cheng, X Xiao - Genomics, 2019 - Elsevier
A cell contains numerous protein molecules. One of the fundamental goals in molecular cell
biology is to determine their subcellular locations since this information is extremely …
biology is to determine their subcellular locations since this information is extremely …
pLoc_bal-mVirus: predict subcellular localization of multi-label virus proteins by Chou's general PseAAC and IHTS treatment to balance training dataset
X Xiao, X Cheng, G Chen, QI Mao… - Medicinal …, 2019 - ingentaconnect.com
Background/Objective: Knowledge of protein subcellular localization is vitally important for
both basic research and drug development. Facing the avalanche of protein sequences …
both basic research and drug development. Facing the avalanche of protein sequences …