We introduce comparative connectomics, the quantitative study of cross-species
commonalities and variations in brain network topology that aims to discover general …

Why has diffusion MRI become a principal modality for mapping connectomes in vivo? How
do different image acquisition parameters, fiber tracking algorithms and other …

Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the
brain, with a range of applications in both clinical and basic neuroscience. Despite …

Tractography based on diffusion MRI offers the promise of characterizing many aspects of
long-distance connectivity in the brain, but requires quantitative validation to assess its …

Connectomes with high sensitivity and high specificity are unattainable with current axonal
fiber reconstruction methods, particularly at the macro-scale afforded by magnetic …

Purpose Human connectomics necessitates high‐throughput, whole‐brain reconstruction of
multiple white matter fiber bundles. Scaling up tractography to meet these high‐throughput …

The fundamental importance of prefrontal cortical connectivity to information processing and,
therefore, disorders of cognition, emotion, and behavior has been recognized for decades …

Anatomic tracing is recognized as a critical source of knowledge on brain circuitry that can
be used to assess the accuracy of diffusion MRI (dMRI) tractography. However, most prior …

Diffusion MRI (dMRI) is a unique tool for the study of brain circuitry, as it allows us to image
both the macroscopic trajectories and the microstructural properties of axon bundles in vivo …

The anterior limb of the internal capsule (ALIC) carries thalamic and brainstem fibers from
prefrontal cortical regions that are associated with different aspects of emotion, motivation …