Uveal melanoma (UM), a rare cancer of the eye, is distinct from cutaneous melanoma by its etiology, the mutation frequency and profile, and its clinical behavior including resistance to …
FC Bidard, J Madic, P Mariani… - … journal of cancer, 2014 - Wiley Online Library
Circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) have been recently investigated in several cancer types, but their respective clinical significance remains to be …
Uveal melanoma (UM) is the most common primary intraocular malignancy affecting adults. Despite successful local treatment of the primary tumour, metastatic disease develops in up …
P Bustamante, L Piquet, S Landreville… - Seminars in cancer …, 2021 - Elsevier
Uveal melanoma (UM) is a type of intraocular tumor with a propensity to disseminate to the liver. Despite the identification of the early driver mutations during the development of the …
DH Im, CC Peng, L Xu, ME Kim, D Ostrow… - International Journal of …, 2022 - mdpi.com
Tumor biopsy can identify prognostic biomarkers for metastatic uveal melanoma (UM), however aqueous humor (AH) liquid biopsy may serve as an adjunct. This study …
MS Parappilly, Y Chin, RM Whalen, AN Anderson… - Cancers, 2022 - mdpi.com
Simple Summary Uveal melanoma is an aggressive cancer that begins in the eye, but often spreads to distant organs when tumor cells enter the blood. Disease spreads in nearly half …
K Sakaizawa, Y Goto, Y Kiniwa, A Uchiyama… - British journal of …, 2012 - nature.com
Background: The availability of molecular-targeted therapies for the treatment of melanoma has emphasised the need to identify mutations in target genes such as BRAF and KIT …
MF Bande Rodríguez, B Fernandez Marta… - Clinical …, 2020 - Taylor & Francis
The detection of metastases in patients with a diagnosis of uveal melanoma (UM) is a controversial issue. While only 1% of the patients have detectable metastases at the time of …
E Jin, JV Burnier - Ocular Oncology and Pathology, 2021 - karger.com
In the era of precision oncology, major strides are being made to use individual tumor information for clinical decision-making. Differing from traditional biopsy methods, the …