Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made
in the elucidation of the pathogenesis of its protean complications, which has inspired recent …

Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

6.2. 2. Wydolność wysiłkowa......................... 1147 6.2. 3. Markery biochemiczne........................
1147 6.2. 4. Kompleksowa ocena rokownicza i oszacowanie ryzyka........................... 1148 6.2 …

Hemolysis is a fundamental feature of sickle cell anemia that contributes to its
pathophysiology and phenotypic variability. Decompartmentalized hemoglobin, arginase 1 …

Pulmonary hypertension is a substantial global health issue. All age groups are affected with
rapidly growing importance in elderly people, particularly in countries with ageing …

Pulmonary hypertension is associated with diverse cardiac, pulmonary, and systemic
diseases in neonates, infants, and older children and contributes to significant morbidity and …

Importance Sickle cell disease (SCD) is a life-threatening genetic disorder affecting nearly
100 000 individuals in the United States and is associated with many acute and chronic …

In 1998, a clinical classification of pulmonary hypertension (PH) was established,
categorizing PH into groups which share similar pathological and hemodynamic …

Since the 1st World Symposium on Pulmonary Hypertension (WSPH) in 1973, pulmonary
hypertension (PH) has been arbitrarily defined as mean pulmonary arterial pressure …

Objective Earlier detection of pulmonary arterial hypertension (PAH), a leading cause of
death in systemic sclerosis (SSc), facilitates earlier treatment. The objective of this study was …