IGF-1, inflammation and retinal degeneration: a close network

AI Arroba, A Campos-Caro… - Frontiers in aging …, 2018 - frontiersin.org
Retinal degenerative diseases are a group of heterogeneous diseases that include age-
related macular degeneration (AMD), retinitis pigmentosa (RP), and diabetic retinopathy …

[HTML][HTML] Anti-VEGF monotherapy versus photodynamic therapy and anti-VEGF combination treatment for neovascular age-related macular degeneration: a meta …

Y Gao, T Yu, Y Zhang, G Dang - Investigative Ophthalmology & …, 2018 - tvst.arvojournals.org
Purpose: The purpose of this study was to compare the efficacy and safety of anti-VEGF
monotherapy with verteporfin photodynamic therapy (PDT) and anti-VEGF combination …

Thermo-responsive PLGA-PEG-PLGA hydrogels as novel injectable platforms for neuroprotective combined therapies in the treatment of retinal degenerative …

JJ López-Cano, A Sigen, V Andrés-Guerrero, H Tai… - Pharmaceutics, 2021 - mdpi.com
The present study aims to develop a thermo-responsive-injectable hydrogel (HyG) based on
PLGA-PEG-PLGA (PLGA= poly-(DL-lactic acid co-glycolic acid); PEG= polyethylene glycol) …

Comparative effectiveness of intravitreal anti-vascular endothelial growth factor therapies for managing neovascular age-related macular degeneration: a meta …

F Matonti, JF Korobelnik, C Dot, V Gualino… - Journal of Clinical …, 2022 - mdpi.com
Intravitreal injections (IVI) of anti-vascular endothelial growth factor (anti-VEGF) have
become the standard of care for age-related macular degeneration (AMD). Although most …

Nonsteroidal anti-inflammatory drugs for retinal neurodegenerative diseases

C Chen, C Wang, X Zhou, L Xu, H Chen, K Qian… - Prostaglandins & Other …, 2021 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most common prescription
drugs for inflammation, and topical NSAIDs are often used in ophthalmology to reduce pain …

Topical ketorolac as an adjunctive treatment with intravitreal bevacizumab in the management of diabetic macular edema: A double-masked placebo-controlled …

H Nikkhah, R Niazpour Moez, M Entezari… - Graefe's Archive for …, 2021 - Springer
Purpose To evaluate the additional effect of ketorolac eye drops on therapeutic effects of
intravitreal Bevacizumab in patients with diabetic macular edema (DME) Methods In a …

Efficacy and vitreous levels of topical NSAIDs

F Semeraro, A Russo, E Gambicorti… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly
prescribed medications and are routinely used for their analgesic, antipyretic, and anti …

Treatment of exudative age‐related macular degeneration with aflibercept combined with pranoprofen eye drops or nutraceutical support with omega‐3: A …

F Semeraro, E Gambicordi, A Cancarini… - British journal of …, 2019 - Wiley Online Library
Aims The aim of this study was to determine whether a combination of intravitreal aflibercept
(IVA) and pranoprofen eyedrops or nutraceutical support provides additional benefit over …

Photodynamic therapy in combination with ranibizumab versus ranibizumab monotherapy for wet age-related macular degeneration: A systematic review and meta …

Y Su, J Wu, Y Gu - Photodiagnosis and photodynamic therapy, 2018 - Elsevier
Objective To evaluate the efficacy and safety between photodynamic therapy (PDT)
combined with intravitreal ranibizumab (IVR) and ranibizumab monotherapy in treating wet …

Combinatorial treatment with topical NSAIDs and anti-VEGF for age-related macular degeneration, a meta-analysis

S Li, A Hu, W Wang, X Ding, L Lu - Plos one, 2017 - journals.plos.org
Inflammation is a key pathogenic factor in age-related macular degeneration (AMD).
However, the clinical importance of combining anti-VEGF agents and topical NSAIDs to …