Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

While scientific advances have led to large-scale production and widespread distribution of
vaccines and antiviral drugs, viruses still remain a major cause of human diseases today …

The de novo design of antimicrobial therapeutics involves the exploration of a vast chemical
repertoire to find compounds with broad-spectrum potency and low toxicity. Here, we report …

Antimicrobial peptides (AMPs), especially antibacterial peptides, have been widely
investigated as potential alternatives to antibiotic-based therapies. Indeed, naturally …

Biofilm-associated infections represent one of the major threats of modern medicine. Biofilm-
forming bacteria are encased in a complex mixture of extracellular polymeric substances …

Abstract Antimicrobial Peptides (AMPs) have been considered as potential alternatives for
infection therapeutics since antibiotic resistance has been raised as a global problem. The …

Plants are extensively used in traditional medicine, and several plant antimicrobial peptides
have been described as potential alternatives to conventional antibiotics. However, after …

Machine learning (ML) consists of the recognition of patterns from training data and offers
the opportunity to exploit large structure–activity databases for drug design. In the area of …

Antimicrobial resistance has become a critical global health problem due to the abuse of
conventional antibiotics and the rise of multi-drug-resistant microbes. Antimicrobial peptides …

In many branches of materials science it is now routine to generate data sets of such large
size and dimensionality that conventional methods of analysis fail. Paradigms and tools from …