Prostate specific membrane antigen (PSMA), is a unique membrane bound glycoprotein,
which is overexpressed manifold on prostate cancer as well as neovasculature of most of …

Iron is vital for almost all living organisms by participating in a wide variety of metabolic
processes, including oxygen transport, DNA synthesis, and electron transport. However, iron …

Glutamic acid is the principal excitatory neurotransmitter in the mammalian central nervous
system. Glutamic acid binds to a variety of excitatory amino acid receptors, which are ligand …

Background Prostate-specific membrane antigen (PSMA) is upregulated in androgen-
dependent prostate carcinoma and it has been targeted for immunotherapy and diagnosis of …

In search of novel genes expressed in metastatic prostate cancer, we subtracted cDNA
isolated from benign prostatic hypertrophic tissue from cDNA isolated from a prostate cancer …

Introduction. The amino acid glutamate is present in high concentrations in the mammalian
brain, and it acts as the major excitatory neurotransmitter in the CNS. Through its actions on …

The transferrin receptor (TfR) undergoes multiple rounds of clathrin-mediated endocytosis
and reemergence at the cell surface, importing iron-loaded transferrin (Tf) and recycling …

Peptide and protein (P/P) drugs have been identified as showing great promises for the
treatment of various neurodegenerative diseases. A major challenge in this regard …

In the progress of science, as in life, timing is important. The acidic dipeptide, N‐
acetylaspartylglutamate (NAAG), was discovered in the mammalian nervous system in 1965 …

Purpose: Previously, we showed successful imaging of xenografts that express the prostate-
specific membrane antigen (PSMA) using small-animal positron emission tomography (PET) …