Antibody‐incorporated nanomedicines for cancer therapy

SY Wu, FG Wu, X Chen - Advanced Materials, 2022 - Wiley Online Library
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …

Anti-tumor strategies by harnessing the phagocytosis of macrophages

SY Li, YL Guo, JW Tian, HJ Zhang, RF Li, P Gong… - Cancers, 2023 - mdpi.com
Simple Summary Macrophages are the “big eaters” of the immune system who are in charge
of engulfing undesirable substances. Macrophages are vital for the human body as they are …

[HTML][HTML] Nanoparticle formulations for therapeutic delivery, pathogen imaging and theranostic applications in bacterial infections

L Jiang, L Ding, G Liu - Theranostics, 2023 - ncbi.nlm.nih.gov
Pathogenic bacterial infections represent an ever-growing crisis, now significantly
threatening life expectancy across the worldwide population and thus novel approaches to …

Clinical implications of inflammation in atheroma formation and novel therapies in cardiovascular diseases

S Barungi, P Hernández-Camarero… - Frontiers in Cell and …, 2023 - frontiersin.org
Cardiovascular diseases (CVD) are the leading causes of death and disability in the world.
Among all CVD, the most common is coronary artery disease (CAD). CAD results from the …

[HTML][HTML] Biopharmaceutical and pharmacokinetic attributes to drive nanoformulations of small molecule tyrosine kinase inhibitors

S Mukherjee, V Joshi, KP Reddy, N Singh… - Asian Journal of …, 2024 - Elsevier
Buoyed by the discovery of small-molecule tyrosine kinase inhibitors (smTKI), significant
impact has been made in cancer chemotherapeutics. However, off-target toxicities and …

[HTML][HTML] CD47-SIRPα axis in cancer therapy: precise delivery of CD47-targeted therapeutics and design of anti-phagocytic drug delivery systems

J Zhu, C Cai, J Li, J Xiao, X Duan - Medicine in Drug Discovery, 2022 - Elsevier
As a “marker of self”, CD47 is expressed on the surface of all cells in humans, mice, and
other mammals to inhibit phagocytic destruction of normal cells through interacting with …

Role of CD47-SIRPα Checkpoint in Nanomedicine-Based Anti-Cancer Treatment

H Liao, C Niu - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
Many cancers have evolved various mechanisms to evade immunological surveillance,
such as the inhibitory immune checkpoint of the CD47-SIRPα signaling pathway. By …

Unlocking Dabrafenib's Potential: A Quality by Design (QBD) Journey to Enhance Permeation and Oral Bioavailability through Nanosponge Formulation

KSC Reddy, D Bhikshapathi, JP Kumar - Brazilian Journal of …, 2025 - SciELO Brasil
This research aims to create dabrafenib (DBF)-loaded nanosponges (NSPs) using β-
cyclodextrin (β-CD) and diphenyl carbonate (DPC) as linker to improve oral bioavailability …

Therapeutic model of vascular regeneration: development of a novel bioreactor for recellularization of human arteries

S Barungi - 2023 - ruja.ujaen.es
We present a study whose main objective is the creation of a therapeutic model of vascular
regeneration using decellularized human arteries. First, the isolation and culture of …