The canonical view of striatal GABAergic interneurons has evolved over several decades of
neuroanatomical/neurochemical and electrophysiological studies. From the anatomical …

The striatum is composed principally of GABAergic, medium spiny striatal projection neurons
(MSNs) that can be categorized based on their gene expression, electrophysiological …

Single-cell gene expression technologies are powerful tools to study cell types in the human
brain, but efforts have largely focused on cortical brain regions. We therefore created a …

Physiological, morphological and immunohistochemical characteristics of non-pyramidal
cells in frontal cortex of young rats were studied in vitro by whole-cell recording and biocytin …

The basal ganglia are a group of subcortical nuclei involved in a variety of processes
including motor, cognitive and mnemonic functions. One of their major roles is to integrate …

We present a biologically plausible model of processing intrinsic to the basal ganglia based
on the computational premise that action selection is a primary role of these central brain …

The basal ganglia play a central role in cognition and are involved in such general functions
as action selection and reinforcement learning. Here, we present a model exploring the …

Many drugs of abuse exert their addictive effects by increasing extracellular dopamine in the
nucleus accumbens, where they likely alter the plasticity of corticostriatal glutamatergic …

The striatum, a major component of the basal ganglia, performs multiple functions including
control of movement, reward, and addiction. Dysfunction and death of striatal neurons are …

The striatum, the largest component of the basal ganglia, contains projection neurons and
interneurons. Whereas there is considerable agreement that the lateral ganglionic eminence …