Riding the metal wave: A review of the latest developments in metal-based anticancer agents
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …
as candidates with great potential for cancer therapy. These agents are effective in a variety …
Hydrazide-hydrazone/hydrazone as enabling linkers in anti-cancer drug discovery: A comprehensive review
S Murugappan, S Dastari, K Jungare, NM Barve… - Journal of Molecular …, 2024 - Elsevier
The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …
safety profiles has spurred the hybridization of various pharmacophores in the past decades …
Interaction of V IV O–8-hydroxyquinoline species with RNase A: the effect of metal ligands in the protein adduct stabilization
G Ferraro, L Vitale, G Sciortino, F Pisanu… - Inorganic Chemistry …, 2023 - pubs.rsc.org
Herein, we studied the interaction of bovine pancreatic ribonuclease (RNase A) with [VIVO
(8-HQ) 2]–a promising antitrypanosomal, antituberculosis, and antitumor vanadium complex …
(8-HQ) 2]–a promising antitrypanosomal, antituberculosis, and antitumor vanadium complex …
[HTML][HTML] Discrete versus polymeric structures of coordination compounds of copper (II) with (pyridin-2-yl) methylenenicotinohydrazide and a library of dicarboxylic …
A series of copper (II) discrete and polymeric coordination compounds, namely [{CuL (H 2
O)} 2 (fum)](1),[{CuL (H 2 O)} 2 (mes)](2),[Cu 2 L 2 (glu)] n· 2n (H 2 O)(3· 2n (H 2 O)) and [Cu …
O)} 2 (fum)](1),[{CuL (H 2 O)} 2 (mes)](2),[Cu 2 L 2 (glu)] n· 2n (H 2 O)(3· 2n (H 2 O)) and [Cu …
Assessment of Mononuclear/Dinuclear copper acylhydrazone complexes for lung cancer treatment
Y Wu, D Wu, J Lan, A Li, L Hou, Y Xu, Y Gou - Bioorganic Chemistry, 2024 - Elsevier
Non-platinum metal-based complexes have good potential for cancer treatment. Here, we
designed and synthesized five hydrazone copper (II) complexes,[Cu 2 (HL) 2 Cl 2] 1A,[Cu 2 …
designed and synthesized five hydrazone copper (II) complexes,[Cu 2 (HL) 2 Cl 2] 1A,[Cu 2 …
Copper (ii) complexes of a furan-containing aroylhydrazonic ligand: syntheses, structural studies, solution chemistry and interaction with HSA
F da Silva Moura, YS Sobrinho, C Stellet… - Dalton …, 2023 - pubs.rsc.org
Copper (II) complexes have become a potential alternative to the use of platinum drugs in
cancer therapy due to their multi-target mode of action. In this context, we report the …
cancer therapy due to their multi-target mode of action. In this context, we report the …
Preparation, characterization, single-crystal analysis, and cytotoxic assessment of complexes formed by Schiff base and 8-hydroxyquinoline co-ligand with Co (II), Ni …
This study focuses on the preparation of mixed ligand complexes of Ni (II), Co (II), and Mn (II)
by combining the co-ligands 2-(((4-fluorophenyl) imino) methyl)-4-methoxy-6-nitrophenol (L …
by combining the co-ligands 2-(((4-fluorophenyl) imino) methyl)-4-methoxy-6-nitrophenol (L …
Design and synthesis of two new thiosemicarbazide based Schiff base metal complexes of nickel (II): DNA binding study and cytotoxicity profile analysis
M Chowdhury, N Biswas, S Saha, BK Biswas… - Inorganica Chimica …, 2025 - Elsevier
Two new nickel (II) substituted thiosemicarbazone Schiff base complexes [Ni (meph)
2](1)[where H 2 meph=(2E)-N-methyl-2-[1-(pyridin-2-yl) ethylidene] hydrazine-1 …
2](1)[where H 2 meph=(2E)-N-methyl-2-[1-(pyridin-2-yl) ethylidene] hydrazine-1 …
Cu (II) and Zn (II) complexes of new 8-hydroxyquinoline Schiff bases: Investigating their structure, solution speciation, and anticancer potential
We report the synthesis and characterization of three novel Schiff bases (L1–L3) derived
from the condensation of 2-carbaldehyde-8-hydroxyquinoline with amines containing …
from the condensation of 2-carbaldehyde-8-hydroxyquinoline with amines containing …
Enhanced selectivity towards melanoma cells with zinc (II)-Schiff bases containing imidazole derivatives
Zinc (II)-complexes with the general formula [Zn (L) 2] containing 8-hydroxyquinoline Schiff
bases functionalized with 1-(3-aminopropyl) imidazole or 1-(3-aminopropyl)-2-methyl-1H …
bases functionalized with 1-(3-aminopropyl) imidazole or 1-(3-aminopropyl)-2-methyl-1H …