The role of vasodilator-stimulated phosphoproteins in the development of malignant tumors

J Gui, H Zhou, H Wan, D Yang, Q Liu… - Current Cancer Drug …, 2024 - benthamdirect.com
Vasodilator-stimulated phosphoprotein (VASP) is an actin-binding protein that includes
three structural domains: Enabled/VASP homolog1 (EVH1), EVH2, and proline-rich (PRR) …

[HTML][HTML] Knockdown of RAC1 and VASP gene expression inhibits breast cancer cell migration

Y Tian, L Xu, Y He, X Xu, K Li, Y Ma… - Oncology …, 2018 - spandidos-publications.com
The ability of tumor cells to migrate is biologically fundamental for tumorigenesis, growth,
metastasis and invasion. The present study examined the role of Ras‑related C3 botulinum …

[HTML][HTML] PKCζ phosphorylates VASP to mediate chemotaxis in breast cancer cells

C Wang, X Zhao, L Zhao, Y Wang, Y Jia… - Experimental Cell …, 2023 - Elsevier
Breast carcinoma (BC) is one of the most common malignant cancers in females, and
metastasis remains the leading cause of death in these patients. Chemotaxis plays an …

Vasodilator-Stimulated Phosphoprotein (VASP) depletion from breast cancer MDA-MB-231 cells inhibits tumor spheroid invasion through downregulation of Migfilin, β …

V Gkretsi, A Stylianou, T Stylianopoulos - Experimental Cell Research, 2017 - Elsevier
A hallmark of cancer cells is their ability to invade surrounding tissues and form metastases.
Cell-extracellular matrix (ECM)-adhesion proteins are crucial in metastasis, connecting …

[HTML][HTML] Bioinformatic approaches to the investigation of the atavistic genes implicated in cancer

A Louka, I Takan, A Pavlopoulou… - Frontiers in Bioscience …, 2021 - imrpress.com
Introduction: Cancer is a widespread phenomenon occurring across multicellular organisms
and represents a condition of atavism, wherein cells follow a path of reverse evolution that …

Inhibition of endothelial nitric oxide synthase in cholangiocarcinoma cell lines–a new strategy for therapy

M Suksawat, A Techasen, N Namwat… - FEBS Open …, 2018 - Wiley Online Library
The isoform of nitric oxide synthase (NOS) found in endothelial cells (eNOS) plays a crucial
role in vasodilation. We recently reported the activation of eNOS in cholangiocarcinoma …

Role of vasodilator‑stimulated phosphoprotein in RANKL‑differentiated murine macrophage RAW264. 7 cells: Modulation of NF‑κB, c‑Fos and NFATc1 transcription …

H Hu, C Li, H Zhang, G Wu… - Experimental and …, 2021 - spandidos-publications.com
Vasodilator‑stimulated phosphoprotein (VASP) is essential for osteoclast differentiation, and
reduced VASP expression results in depressed osteoclast differentiation. Previously, we …

Role of vasodilator‑stimulated phosphoprotein in human cytomegalovirus‑induced hyperpermeability of human endothelial cells

Y Tian, Y He, L Zhang, J Zhang… - Experimental and …, 2018 - spandidos-publications.com
Atherosclerosis (AS) is a common chronic vascular disease and epidemiological evidence
demonstrates that infection is closely associated with the occurrence of AS, including …

Protein kinase G-Iα hyperactivation and VASP phosphorylation in promoting ovarian cancer cell migration and platinum resistance

JC Wong, RR Fiscus - Ovarian Cancer-A Clin Transl Update …, 2013 - books.google.com
Platinum-based drugs such as cisplatin (cis-diammine-dichloro-platinum, also commonly
known as CDDP) have dominated the drug therapy of ovarian cancer during the past three …

[图书][B] The large Maf transcription factor Traffic jam regulates collective cell migration during Drosophila oogenesis

F Gunawan - 2015 - search.proquest.com
Collective cell migration is a fundamental process throughout development. The migrating
border cell cluster (BCC) in the Drosophila ovary is a good in-vivo model system to study this …