Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …

Albumin is the most abundant circulating protein in plasma and has recently emerged as a
versatile protein carrier for drug targeting and for improving the pharmacokinetic profile of …

Bioorthogonal chemistry capable of operating in live animals is needed to investigate
biological processes such as cell death and immunity. Recent studies have identified a …

18F-fluorination is an important and growing field in organic synthesis that has attracted
many chemists in the recent past. Here we present our own, biased perspective with a focus …

The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

When we critically assess the reason for the current dominance of 68Ga-labeled peptides
and peptide-like ligands in radiopharmacy and nuclear medicine, we have to conclude that …

The lack of efficient [18F] fluorination processes and target-specific organofluorine
chemotypes remains the major challenge of fluorine-18 positron emission tomography …

Given the unique properties of fluorine, and the ability of fluorination to change the
properties of organic molecules, there is significant interest from medicinal chemists in …

Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals,
volume four in Alain Tressaud's Progress in Fluorine Science series, presents a critical …

Radiolabeled peptides have been the subject of intense research efforts for targeted
diagnostic imaging and radiotherapy over the last 20 years. Peptides offer several …