The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …

Covering: 1965–2014 Fungi (Ascomycota and Basidiomycota) are prolific producers of
structurally diverse terpenoid compounds. Classes of terpenoids identified in fungi include …

Covering: up to February 2012 The complexity of terpenoid natural products has drawn
significant interest, particularly since their common (poly) isoprenyl origins were discovered …

<? xm-replace_text {Heading}?> Abstract Tens of thousands of terpenoid natural products
have been isolated from plants and microbial sources. Higher fungi (Ascomycota and …

Covering: up to July 2011 Sesquiterpene synthases catalyse the metal dependent turnover
of farnesyl diphosphate to generate a class of natural products characterised by an …

The X-ray crystal structure of recombinant epi-isozizaene synthase (EIZS), a sesquiterpene
cyclase from Streptomyces coelicolor A3 (2), has been determined at 1.60 Å resolution …

Terpenes constitute the largest and structurally most diverse natural product family. Most
terpenoids exhibit a stereochemically complex macrocyclic core, which is generated by C–C …

The X-ray crystal structure of recombinant PcISPS (isoprene synthase from gray poplar
hybrid Populus× canescens) has been determined at 2.7 Å resolution, and the structure of its …

(+)-δ-Cadinene synthase (DCS) from Gossypium arboreum (tree cotton) is a sesquiterpene
cyclase that catalyzes the cyclization of farnesyl diphosphate in the first committed step of …