The central function of the immune system is to protect the host from environmental agents
such as microbes or chemicals, thereby preserving the integrity of the body, and preventing …

Kinin B 1 and B 2 receptors are central to the aetiology of pain and inflammation.
Constitutive B 2 receptors are commonly associated with the acute phase of inflammation …

The Kallikrein-Kinin System (KKS) has been associated to inflammatory and immunogenic
responses in the peripheral and central nervous system by the activation of two receptors …

Background and purpose: We investigated whether or not kinin receptors play a role in
diabetic blood–retinal barrier breakdown, which is a leading cause of vision loss …

Introduction: Kinins are bioactive peptide hormones that exert biological effects by activating
two types of G protein-coupled receptors namely, B1 (B1R) and B2 (B2R). These modulate …

Background Kinin B 1 receptors are inducible molecules up-regulated after inflammatory
stimuli. This study evaluated the relevance of kinin B 1 receptors in a mouse depression …

Although numerous inflammation pathways have been implicated in Alzheimer's disease,
the involvement of the kallikrein–kinin system is still under investigation. We anatomically …

Mammalian bombesin (Bn) receptors comprise 3 subtypes: BB 1, BB 2, BB 3 (nomenclature
recommended by the NC-IUPHAR Subcommittee on bombesin receptors,[109]). BB 1 and …

Diabetes Mellitus leads to pain neuropathy and cardiovascular complications which remain
resistant to current therapies involving the control of glycaemia. This study aims at defining …

Objective. The aim of the study was to investigate the expression patterns of a specific set of
genes involved in the inflammation process in children with Down Syndrome (DS) and …