Intermediate filaments play a pivotal role in regulating cell architecture and function

J Lowery, ER Kuczmarski, H Herrmann… - Journal of Biological …, 2015 - ASBMB
Intermediate filaments (IFs) are composed of one or more members of a large family of
cytoskeletal proteins, whose expression is cell-and tissue type-specific. Their importance in …

Intermediate filaments: from cell architecture to nanomechanics

H Herrmann, H Bär, L Kreplak, SV Strelkov… - … reviews Molecular cell …, 2007 - nature.com
Intermediate filaments (IFs) constitute a major structural element of animal cells. They build
two distinct systems, one in the nucleus and one in the cytoplasm. In both cases, their major …

Unique role of vimentin networks in compression stiffening of cells and protection of nuclei from compressive stress

K Pogoda, F Byfield, P Deptuła, M Cieśluk… - Nano Letters, 2022 - ACS Publications
In this work, we investigate whether stiffening in compression is a feature of single cells and
whether the intracellular polymer networks that comprise the cytoskeleton (all of which stiffen …

The cell as a material

KE Kasza, AC Rowat, J Liu, TE Angelini… - Current opinion in cell …, 2007 - Elsevier
To elucidate the dynamic and functional role of a cell within the tissue it belongs to, it is
essential to understand its material properties. The cell is a viscoelastic material with highly …

[图书][B] Introduction to proteins: structure, function, and motion

A Kessel, N Ben-Tal - 2018 - taylorfrancis.com
Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

Intermediate filaments: primary determinants of cell architecture and plasticity

H Herrmann, SV Strelkov, P Burkhard… - The Journal of clinical …, 2009 - Am Soc Clin Investig
Intermediate filaments (IFs) are major constituents of the cytoskeleton and nuclear boundary
in animal cells. They are of prime importance for the functional organization of structural …

Nanoindentation of soft biological materials

L Qian, H Zhao - Micromachines, 2018 - mdpi.com
Nanoindentation techniques, with high spatial resolution and force sensitivity, have recently
been moved into the center of the spotlight for measuring the mechanical properties of …

Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm

S Kim, PA Coulombe - Genes & development, 2007 - genesdev.cshlp.org
Intermediate filaments (IFs) are cytoskeletal polymers whose protein constituents are
encoded by a large family of differentially expressed genes. Owing in part to their properties …

Structural and regulatory functions of keratins

TM Magin, P Vijayaraj, RE Leube - Experimental cell research, 2007 - Elsevier
The diversity of epithelial functions is reflected by the expression of distinct keratin pairs that
are responsible to protect epithelial cells against mechanical stress and to act as signaling …

Mechanical response of cytoskeletal networks

ML Gardel, KE Kasza, CP Brangwynne, J Liu… - Methods in cell …, 2008 - Elsevier
The cellular cytoskeleton is a dynamic network of filamentous proteins, consisting of
filamentous actin (F‐actin), microtubules, and intermediate filaments. However, these …