Sex differences and the endocannabinoid system in pain

HL Blanton, RC Barnes, MC McHann, JA Bilbrey… - Pharmacology …, 2021 - Elsevier
Cannabis use has been increasing in recent years, particularly among women, and one of
the most common uses of cannabis for medical purposes is pain relief. Pain conditions and …

Female chemical signalling underlying reproduction in mammals

HA Coombes, P Stockley, JL Hurst - Journal of chemical ecology, 2018 - Springer
Chemical communication plays many key roles in mammalian reproduction, although
attention has focused particularly on male scent signalling. Here, we review evidence that …

Ethanol extract of the mushroom Coprinus comatus exhibits antidiabetic and antioxidant activities in streptozotocin-induced diabetic rats

NI Ratnaningtyas, H Hernayanti, N Ekowati… - Pharmaceutical …, 2022 - Taylor & Francis
Context Edible mushrooms have a long history of use in traditional Chinese or Japanese
medicine. Coprinus comatus (OF Müll.) Pers.(Agaricaceae) contains antioxidant and …

Kisspeptin modulates sexual and emotional brain processing in humans

AN Comninos, MB Wall, L Demetriou… - The Journal of …, 2017 - Am Soc Clin Investig
BACKGROUND. Sex, emotion, and reproduction are fundamental and tightly entwined
aspects of human behavior. At a population level in humans, both the desire for sexual …

High efficacy, rapid onset nanobiolosomes of sildenafil as a topical therapy for erectile dysfunction in aged rats

LR Abdelalim, OY Abdallah, YSR Elnaggar - International Journal of …, 2020 - Elsevier
Developing topical sildenafil for local treatment of erectile dysfunction has been of great
interest in pharmaceutical research. Sildenafil citrate (SC) exhibited a well-documented …

Withania somnifera ameliorates sexual arousal and impotence in stressed sexually sluggish male rats by modulating neurotransmitters and NO/cGMP/PDE5α …

A Yadav, RK Mishra - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Psychological stress is a growing global threat to male
sexual potency and erection efficiency. Withania somnifera (L.) Dunal (WS), also known as …

Effects of apelin on reproductive functions: relationship with feeding behavior and energy metabolism

S Tekin, Y Erden, S Sandal… - … of physiology and …, 2017 - Taylor & Francis
Apelin is an adipose tissue derived peptidergic hormone. In this study, 40 male Sprague–
Dawley rats were used (four groups; n= 10). Apelin-13 at three different dosages (1, 5 and …

Social behavior, hormones and adult neurogenesis

M Opendak, BA Briones, E Gould - Frontiers in neuroendocrinology, 2016 - Elsevier
A variety of experiences have been shown to affect the production of neurons in the adult
hippocampus. These effects may be mediated by experience-driven hormonal changes …

[HTML][HTML] Kisspeptin enhances brain responses to olfactory and visual cues of attraction in men

L Yang, L Demetriou, MB Wall, EGA Mills, D Zargaran… - JCI insight, 2020 - ncbi.nlm.nih.gov
Successful reproduction is a fundamental physiological process that relies on the integration
of sensory cues of attraction with appropriate emotions and behaviors and the reproductive …

[HTML][HTML] Cannabigerol reduces acute and chronic hypernociception in animals exposed to prenatal hypoxia-ischemia

B Rezende, KL Marques, FEA de Carvalho… - Scientia …, 2024 - mdpi.com
Cannabigerol (CBG), a phytocannabinoid, has shown promise in pain management.
Previous studies by our research group identified an increase in pain sensitivity as a …