The limited regenerative capacity of the human body, in conjunction with a shortage of
healthy autologous tissue, has created an urgent need for alternative grafting materials. A …

Podocytes form the backbone of the glomerular filtration barrier and are exposed to various
mechanical forces throughout the lifetime of an individual. The highly dynamic …

Recreating human tissues and organs in the petri dish to establish models as tools in
biomedical sciences has gained momentum. These models can provide insight into …

Three-dimensional cell culture technology (3DCC) sits between two-dimensional cell culture
(2DCC) and animal models and is widely used in oncology research. Compared to 2DCC …

The use of animal models in therapeutic development has long been the standard practice.
However, ethical concerns and the inherent species differences have prompted a …

Kidney diseases with kidney failure or damage, such as chronic kidney disease (CKD) and
acute kidney injury (AKI), are common clinical problems worldwide and have rapidly …

Kidney disease encompasses a wide spectrum of conditions, ranging from simple infections
to chronic kidney disease. When the kidneys are unable to filter blood and remove waste …

Complexation with sulfated glycosaminoglycans (GAGs) regulates the signaling of pro‐
angiogenic growth factors in vivo. To use this principle in modulating microvascular network …

Recent advancements in vascular organoid (VO) and vessel-on-chip (VoC) technologies
have revolutionized our approach to studying human diseases, offering unprecedented …

To date, genetically modified organoids are emerging as a promising 3D modeling tool
aimed at solving genetically relevant clinical and biomedical problems for regenerative …