Calcineurin inhibitors (CNIs) are both the savior and Achilles' heel of kidney transplantation.
Although CNIs have significantly reduced rates of acute rejection, their numerous toxicities …

Metabolic acidosis is fairly common in patients with chronic kidney disease (CKD). The
prevalence of metabolic acidosis increases with worsening kidney function and is observed …

Background Metabolic acidosis is common in kidney transplant recipients and is associated
with declining graft function. Sodium bicarbonate treatment effectively corrects metabolic …

Rationale & Objective Studies showing an association between lower bicarbonate levels
and worse kidney disease prognosis have not accounted for the influence of pH. It remains …

Rationale & Objective Metabolic acidosis related to chronic kidney disease (CKD) is
associated with an accelerated decline in glomerular filtration rate (GFR) and the …

Background: There is conflicting information on current medical and surgical complications
associated with high body mass index (BMI) after kidney transplantation. Methods: In a …

Background: Metabolic acidosis (MA) is a common complication in kidney transplantation
(KTx). It is more prevalent in KTx than in CKD, and it occurs at higher glomerular filtration …

Background Poor linear growth is a consequence of chronic kidney disease (CKD) that has
been linked to adverse outcomes. Metabolic acidosis (MA) has been identified as a risk …

Background Metabolic acidosis is a risk factor for faster kidney function decline in chronic
kidney disease (CKD) and in adult kidney transplant recipients (KTRs). We hypothesized …

Background Studies examining associations between metabolic acidosis and
cardiovascular events in chronic kidney disease (CKD) have shown conflicting results and …