[HTML][HTML] Kidney injury molecule 1 (KIM-1): a multifunctional glycoprotein and biological marker

ТА Karmakova, NS Sergeeva, КY Kanukoev… - Современные …, 2021 - cyberleninka.ru
KIM-1 (kidney injury molecule 1) is a transmembrane glycoprotein also known as HAVcr-1
and TIM-1 belongs to the T-cell immunoglobulin and mucin domain family (TIM) of proteins …

[PDF][PDF] Sensing dying cells in health and disease: the importance of kidney injury molecule-1

E Tutunea-Fatan, S Arumugarajah… - Journal of the …, 2024 - journals.lww.com
Abstract Kidney Injury Molecule-1 (KIM-1), also known as T cell immunoglobulin and mucin
domain-1 (TIM-1), is a widely recognized biomarker for acute kidney injury, but its biological …

KIM-1 as a blood-based marker for early detection of kidney cancer: a prospective nested case–control study

G Scelo, DC Muller, E Riboli, M Johansson… - Clinical Cancer …, 2018 - AACR
Purpose: Renal cell carcinoma (RCC) has the potential for cure with surgery when
diagnosed at an early stage. Kidney injury molecule-1 (KIM-1) has been shown to be …

Plasma KIM-1 is associated with recurrence risk after nephrectomy for localized renal cell carcinoma: A trial of the ECOG-ACRIN Research Group (E2805)

W Xu, M Puligandla, B Halbert, NB Haas… - Clinical Cancer …, 2021 - AACR
Purpose: No circulating biomarkers are currently available to identify patients at highest risk
of recurrence after nephrectomy for renal cell carcinoma (RCC). Kidney injury molecule-1 …

Prognostic value of TIM-1 expression in human non-small-cell lung cancer

X Zheng, K Xu, L Chen, Y Zhou, J Jiang - Journal of translational medicine, 2019 - Springer
Background T-cell immunoglobulin and mucin domain 1 (TIM-1) is an important co-
stimulatory molecule which serves as a surface marker for T cell activation, especially for …

Cytochrome C inhibits tumor growth and predicts favorable prognosis in clear cell renal cell carcinoma

Z Liu, X Zhao, L Zhang, B Pei - Oncology letters, 2019 - spandidos-publications.com
Abstract Cytochrome C (Cyto C), a multifunctional enzyme, has been demonstrated to be
associated with cell apoptosis and respiration. Accumulating evidence has revealed that …

Role of TIM-1 in the development and treatment of tumours

J Cao, J Qing, L Zhu, Z Chen - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
T-cell immunoglobulin and mucin structural domain 1 (TIM-1, also known as hepatitis A virus
cell receptor 1) is a co-stimulatory molecule that is expressed predominantly on the surface …

Kidney injury molecule-1; is it a predictive marker for renal diseases?

DG Anandkumar, PC Dheerendra… - Journal of …, 2023 - jnephropharmacology.com
Kidney injury is the main cause of mortality and morbidity globally. The kidney injury
molecule (KIM-1) is a type 1 transmembrane protein, which is been upregulated during renal …

Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma

JC Lee, DM Yotis, JY Lee, MA Sarabusky, B Shrum… - Scientific Reports, 2021 - nature.com
Metastasis is present in approximately 30% of patients diagnosed with renal cell carcinoma
(RCC) and is associated with a 5-year survival rate of< 15%. Kidney injury molecule 1 (KIM …

Diagnostic role of kidney injury molecule-1 in renal cell carcinoma

KJ Zhang, GD Wilson, S Kara, A Majeske… - … urology and nephrology, 2019 - Springer
Despite rapid advances in diagnostic and therapeutic medicine, renal cell carcinoma (RCC)
continues to cause significant morbidity and mortality in patients. While there has been a …