Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
A review on recent approaches on molecular docking studies of novel compounds targeting acetylcholinesterase in Alzheimer disease
SC Peitzika, E Pontiki - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
Discovery of sulfadrug–pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors
Human carbonic anhydrase (hCA) isoenzymes are zinc ion‐containing, widespread
metalloenzymes and they classically play a role in pH homeostasis maintenance. CA …
metalloenzymes and they classically play a role in pH homeostasis maintenance. CA …
[HTML][HTML] Photocatalytic degradation of Rhodamine B (RhB) dye in waste water and enzymatic inhibition study using cauliflower shaped ZnO nanoparticles synthesized …
Abstract The ZnO nanoparticles (NPs) are considered to be one of the inexpensive and very
important bioactive materials widely used in drug delivery, as a photo-catalyst material …
important bioactive materials widely used in drug delivery, as a photo-catalyst material …
[HTML][HTML] Synthesis and inhibition profiles of N-benzyl-and N-allyl aniline derivatives against carbonic anhydrase and acetylcholinesterase–A molecular docking study
The alkyl and aryl derivatives of aniline are important starting materials in fine organic
synthesis. Allyl bromide and benzyl chloride were taken as substrates for the alkylation …
synthesis. Allyl bromide and benzyl chloride were taken as substrates for the alkylation …
Novel 2-aminopyridine liganded Pd (II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties
In this work, the synthesis, crystal structure, characterization, and enzyme inhibition effects of
the novel a series of 2-aminopyridine liganded Pd (II) N-heterocyclic carbene (NHC) …
the novel a series of 2-aminopyridine liganded Pd (II) N-heterocyclic carbene (NHC) …
Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors
A series of substituted pyrazole compounds (1–8 and 9a, b) were synthesized and their
structure was characterized by IR, NMR, and Mass analysis. These obtained novel pyrazole …
structure was characterized by IR, NMR, and Mass analysis. These obtained novel pyrazole …
[HTML][HTML] Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS
Many chronic diseases such as diabetes and Alzheimer's disease are related to the type
and quality of foods, which are consumed. Particularly, various plant origin products are …
and quality of foods, which are consumed. Particularly, various plant origin products are …
The synthesis of novel unnatural amino acid by intramolecular aza‐Michael addition reaction as multitarget enzyme inhibitors
Synthesis of novel unnatural amino acids (UAAs) from 4‐oxo‐4‐phenylbut‐2‐enoic acid
derivatives with intramolecular aza‐Michael addition reaction in the presence of …
derivatives with intramolecular aza‐Michael addition reaction in the presence of …
Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and …
The synthesis, characterization and biological evaluation of a series of novel N-substituted
phthalazine sulfonamide (5a-l) are disclosed. Phthalazines which are nitrogen-containing …
phthalazine sulfonamide (5a-l) are disclosed. Phthalazines which are nitrogen-containing …