With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Microglia are the brain's resident macrophages, which guide various developmental
processes crucial for brain maturation, activity, and plasticity. Microglial progenitors enter the …

Importance Synaptic dysfunction is involved in schizophrenia pathophysiology. However,
whether in vivo synaptic density is reduced in early stages of psychosis, including its high …

Background Schizophrenia (SCZ) is a severe neuropsychiatric disorder of complex, poorly
understood etiology, associated with both genetic and environmental factors. De novo …

Background The study of neurons is fundamental to unraveling the complexities of the
nervous system. Primary neuronal cultures from rodents have long been a cornerstone of …

There has been a recent drive to replace in vivo studies with in vitro studies in the field of
toxicity testing. Therefore, instead of conventional animal or planar cell culture models, there …

Discovery and validation of new, reliable diagnostic and predictive biomarkers for
schizophrenia (SCZ) are an ongoing effort. Here, we assessed the mRNA expression and …

The modeling of psychiatric disorders poses significant challenges due to the complex
nature of these conditions, which encompass a range of neuropsychiatric diseases such as …

Treatment of Schizophrenia Using Lithium Chloride, a Ketogenic Diet, and Stem Cell
Transplantation Page 1 IJMS Vol 49, No 11, November 2024 Copyright: ©Iranian Journal of …

Limited therapeutic advancements in Schizophrenia (SCZ) depend on the heterogeneous
nature of the disorder, impacting drug development and clinical trials that assume uniform …