Helicobacter pylori is a class one carcinogen which causes chronic atrophic gastritis, gastric
intestinal metaplasia, dysplasia and adenocarcinoma. The mechanisms by which H. pylori …

Epigenetic modulation of gene activity occurs in response to non-genetic factors such as
body weight status, physical activity, dietary factors, and environmental toxins. In addition …

Epigenetic mechanisms regulate expression of the genome to generate various cell types
during development or orchestrate cellular responses to external stimuli. Recent studies …

Research on obesity-and diabetes mellitus (DM)-related carcinogenesis has expanded
exponentially since these two diseases were recognized as important risk factors for …

Epigenetic modifications occur in response to environmental changes and play a
fundamental role in gene expression following environmental stimuli. Major epigenetic …

Objective Helicobacter pylori infection is mostly a family-based infectious disease. To
facilitate its prevention and management, a national consensus meeting was held to review …

The term 'field effect'(also known as field defect, field cancerization, or field carcinogenesis)
has been used to describe a field of cellular and molecular alteration, which predisposes to …

Helicobacter pylori infection causes chronic gastritis, which can progress to severe
gastroduodenal pathologies, including peptic ulcer, gastric cancer and gastric mucosa …

DNA damage and repair are linked to cancer. DNA damage that is induced endogenously or
from exogenous sources has the potential to result in mutations and genomic instability if not …

Disparate occurrence of breast cancer remains an intriguing question since only a subset of
women with known risk factors develop cancer. Recent studies suggest an active role of …