Aging is characterized by a progressive loss of tissue and organ function due to genetic and
environmental factors, nutrition, and lifestyle. Oxidative stress is one the most important …

Adipose tissue is a dynamic and metabolically active organ that plays a crucial role in
energy homeostasis and endocrine function. Recent advancements in lipidomics techniques …

Lipids can be of endogenous or exogenous origin and affect diverse biological functions,
including cell membrane maintenance, energy management and cellular signalling. Here …

Lipid analysis at the molecular species level represents a valuable opportunity for clinical
applications due to the essential roles that lipids play in metabolic health. However, a …

Lipidomics as a branch of metabolomics provides unique information on the complex lipid
profile in biological materials. In clinically focused studies, hundreds of lipids together with …

Cardiovascular diseases (CVD) are the leading cause of death worldwide for both men and
women, but their prevalence and burden show marked sex differences. The existing …

Metabolites that mark aging are not fully known. We analyze 408 plasma metabolites in
Long Life Family Study participants to characterize markers of age, aging, extreme longevity …

The levels of blood eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are very
variable and, in general, low in most of the world population. In this study, the effects of age …

As one of the OMICS in systems biology, metabolomics defines the metabolome and
simultaneously quantifies numerous metabolites that are final or intermediate products and …

Osteoarthritis (OA) is a major disease whose prevalence increases with aging, sedentary
lifestyles, and obesity. The association between obesity and OA has been well documented …