A review on adducin from functional to pathological mechanisms: future direction in cancer

KMY Kiang, GKK Leung - BioMed Research International, 2018 - Wiley Online Library
Adducin (ADD) is a family of membrane skeleton proteins including ADD1, ADD2, and
ADD3 that are encoded by distinct genes on different chromosomes. Adducin is primarily …

Loss of cytoskeleton protein ADD3 promotes tumor growth and angiogenesis in glioblastoma multiforme

KMY Kiang, P Zhang, N Li, Z Zhu, L Jin, GKK Leung - Cancer letters, 2020 - Elsevier
Abstract Adducin 3 (ADD3) is a crucial assembly factor in the actin cytoskeleton and has
been found to be aberrantly expressed in various cancers, including glioblastoma …

[HTML][HTML] Adducin in tumorigenesis and metastasis

C Luo, J Shen - Oncotarget, 2017 - ncbi.nlm.nih.gov
Adducin is a membrane-skeletal protein localized at spectrin-actin junctions, involving in the
formation of the network of cytoskeleton, cellular signal transduction, ionic transportation …

Reconfiguring phosphorylation signaling by genetic polymorphisms affects cancer susceptibility

Y Wang, H Cheng, Z Pan, J Ren, Z Liu… - Journal of molecular …, 2015 - academic.oup.com
Large-scale sequencing has characterized an enormous number of genetic variations
(GVs), and the functional analysis of GVs is fundamental to understanding differences in …

A Phosphorylation-Related Variant ADD1-rs4963 Modifies the Risk of Colorectal Cancer

N Shen, C Liu, J Li, X Chen, Y Yang, Y Zhu, Y Gong… - PLoS …, 2015 - journals.plos.org
It is well-established that abnormal protein phosphorylation could play an essential role in
tumorgenesis by disrupting a variety of physiological processes such as cell growth, signal …

Increased expression of phosphorylated adducin in tumor cells

C Luo, G Wang, H Ying, J Shen… - Journal of International …, 2020 - journals.sagepub.com
Objective This preclinical research was designed to study the phosphorylation level of
adducin in cancer tissues, healthy tissues, and malignant tumor cells to determine the …