Enantiomers, where chirality arises from restricted rotation around a single bond, are
atropisomers. Due to the unique nature of the origins of their chirality, synthetic strategies to …

Conspectus Atropisomers bearing a rotation-restricted axis are common structural units in
natural products, chiral ligands, and drugs; thus, the prevalence of asymmetric synthesis has …

Atropisomers beyond the C–C axis (denoted as X–Y herein) are important addition to the
repertoire of axially chiral compounds, which have received much attention in recent years …

Enantioselective redox transformations typically rely on costly transition metals as catalysts
and often stoichiometric amounts of chemical redox agents as well. Electrocatalysis …

Molecules with restricted rotation around a single bond or atropisomers are found in a wide
number of natural products and bioactive molecules as well as in chiral ligands for …

Atropisomeric C–N compounds belong to an important class of axially chiral compounds.
However, whereas the asymmetric synthesis of biaryl atropisomers have been well …

The catalytic asymmetric construction of N− N atropisomeric biaryls remains a formidable
challenge. Studies of them lag far behind studies of the more classical carbon‐carbon biaryl …

Transition-metal catalyzed C–H activation reactions have been proven to be useful
methodologies for the assembly of synthetically meaningful molecules. This approach bears …

Enantioselective C− H activation has surfaced as a transformative toolbox for the efficient
assembly of chiral molecules. However, despite of major advances in rhodium and …

In recent years, asymmetric catalysis of ynamides has attracted much attention, but these
reactions mostly constructed central chirality, except for a few examples on the synthesis of …