The natural products of heterobranch molluscs display a huge variability both in structure
and in their bioactivity. Despite the considerable lack of information, it can be observed from …

The species diversity of marine heterobranch sea slugs found on field trips around Bunaken
Island (North Sulawesi, Indonesia) and adjacent islands of the Bunaken National Marine …

Mitochondria are the target sites for multiple disease manifestations, for which it is appealing
to researchers' attention for advanced pharmacological interventions. Mitochondrial …

We describe herein a concise synthesis of (+)‐neopeltolide, a marine macrolide natural
product that elicits a highly potent antiproliferative activity against several human cancer cell …

The NMR-directed investigation of the New Zealand marine sponge Hamigera tarangaensis
has afforded ten new compounds of the hamigeran family, and a new 13-epi-verrucosane …

A protecting group-free strategy is presented for diastereo-and enantioselective routes that
can be used to prepare a wide variety of Z-homoallylic alcohols with significantly higher …

The inadequate vascularization seen in fast-growing solid tumors gives rise to hypoxic
areas, fostering specific changes in gene expression that bolster tumor cell survival and …

Herein we designed a collection of trimethyl-lock quinone profluorophores as activity-based
probes for imaging NAD (P) H: quinone oxidoreductase (NQO1) in cancer cells and tumour …

Background: Marine environment constitutes an almost infinite resource for novel anticancer
drug discovery. The biodiversity of marine organisms provides a rich source for the …

Scale-up isolation of (+)-(5 Z)-(8 S)-(14 Z)-mycothiazole (1) from Vanuatu specimens of C.
mycofijiensis to semisynthesize (+)-(5 Z)-(8 S)-8-O-acetyl-(14 Z)-mycothiazole (2) revealed a …