The chemistry and biochemistry of vanadium and the biological activities exerted by vanadium compounds

DC Crans, JJ Smee, E Gaidamauskas… - Chemical reviews, 2004 - ACS Publications
Vanadium is a trace element, which may be beneficial and possibly essential in humans1
but certainly essential for some living organisms. 2r11 Metal ions and thus vanadium ions …

Salan vs. salen metal complexes in catalysis and medicinal applications: Virtues and pitfalls

JC Pessoa, I Correia - Coordination Chemistry Reviews, 2019 - Elsevier
Salen complexes are widely employed in catalysis and biomedical science and chiral salen
complexes are among the most important catalysts for asymmetric synthesis. Their reduced …

Vanadium ionic species from degradation of Ti-6Al-4V metallic implants: In vitro cytotoxicity and speciation evaluation

BC Costa, CK Tokuhara, LA Rocha, RC Oliveira… - Materials Science and …, 2019 - Elsevier
Among the metallic materials used in biomedical industry, the most common choice for
orthopedics and dental implants is titanium (Ti) and its alloys, mainly due to their superior …

Speciation of metal drugs, supplements and toxins in media and bodily fluids controls in vitro activities

A Levina, DC Crans, PA Lay - Coordination Chemistry Reviews, 2017 - Elsevier
Studies of metal uptake, metabolism and excretion by single bacterial, yeast, plant and
animal cells is a widespread area of research, yet little is known about the reactivity and …

Vanadium in diabetes: 100 years from Phase 0 to Phase I

KH Thompson, C Orvig - Journal of inorganic biochemistry, 2006 - Elsevier
A little over one hundred years ago, a vanadium-containing compound was assessed
clinically for use in treatment of human diabetic patients. The results were somewhat …

Biological and medicinal aspects of vanadium

D Rehder - Inorganic Chemistry Communications, 2003 - Elsevier
The importance of vanadium in life processes is addressed, emphasising the vanadium
cofactors in vanadate-dependent haloperoxidases and vanadium-nitrogenases. Structural …

Developing vanadium as an antidiabetic or anticancer drug: A clinical and historical perspective

DC Crans, L Henry, G Cardiff, BI Posner - Met. Ions Life Sci, 2019 - degruyter.com
Vanadium has been known for centuries to have beneficial effects on health and has the
potential to be used as an alternative to other diabetic and anticancer medicines. The …

Anti-diabetic effects of a series of vanadium dipicolinate complexes in rats with streptozotocin-induced diabetes

GR Willsky, LH Chi, M Godzala III, PJ Kostyniak… - Coordination Chemistry …, 2011 - Elsevier
The effects of oral treatment of rats with streptozotocin-induced diabetes with a range of
vanadium dipicolinate complexes (Vdipic) and derivatives are reviewed. Structure–reactivity …

Therapeutic properties of vanadium complexes

AA Sharfalddin, IM Al-Younis, HA Mohammed… - Inorganics, 2022 - mdpi.com
Vanadium is a hard, silver-grey transition metal found in at least 60 minerals and fossil fuel
deposits. Its oxide and other vanadium salts are toxic to humans, but the toxic effects depend …

Antidiabetic, chemical, and physical properties of organic vanadates as presumed transition-state inhibitors for phosphatases

DC Crans - The Journal of Organic Chemistry, 2015 - ACS Publications
Studies of antidiabetic vanadium compounds, specifically the organic vanadate esters, are
reviewed with regard to their chemistry and biological properties. The compounds are …