[HTML][HTML] Lipocalin-2: Structure, function, distribution and role in metabolic disorders

S Al Jaberi, A Cohen, C D'Souza… - Biomedicine & …, 2021 - Elsevier
Abstract Lipocalin-2 (LCN-2) is a novel, 198 amino acid adipocytokine also referred to as
neutrophil gelatinase-associated lipocalin (NGAL). LCN-2 is a circulatory protein …

The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases

V Abella, M Scotece, J Conde, R Gómez, A Lois… - Biomarkers, 2015 - Taylor & Francis
Abstract Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin
(NGAL), is a secreted glycoprotein that belongs to a group of transporters of small lipophilic …

[HTML][HTML] Lipocalin 2 as a link between ageing, risk factor conditions and age-related brain diseases

DW Dekens, ULM Eisel, L Gouweleeuw… - Ageing research …, 2021 - Elsevier
Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

The bones of children with obesity

D Fintini, S Cianfarani, M Cofini, A Andreoletti… - Frontiers in …, 2020 - frontiersin.org
Excess adiposity in childhood may affect bone development, ultimately leading to bone
frailty. Previous reports showing an increased rate of extremity fractures in children with …

Cellular and molecular mechanisms associating obesity to bone loss

YS Forte, M Renovato-Martins, C Barja-Fidalgo - Cells, 2023 - mdpi.com
Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

[HTML][HTML] Role of lipocalin 2 in stroke

RY Zhao, PJ Wei, X Sun, DH Zhang, QY He, J Liu… - Neurobiology of …, 2023 - Elsevier
Stroke is the second leading cause of death worldwide; however, the treatment choices
available to neurologists are limited in clinical practice. Lipocalin 2 (LCN2) is a secreted …

Lipocalin 2 (LCN2) expression in hepatic malfunction and therapy

A Asimakopoulou, S Weiskirchen… - Frontiers in …, 2016 - frontiersin.org
Lipocalin 2 (LCN2) is a secreted protein that belongs to the Lipocalins, a group of
transporters of small lipophilic molecules such as steroids, lipopolysaccharides, iron, and …

REPIN1 regulates iron metabolism and osteoblast apoptosis in osteoporosis

Y Xia, G Ge, H Xiao, M Wu, T Wang, C Gu… - Cell Death & …, 2023 - nature.com
Osteoporosis is not well treated due to the difficulty of finding commonalities between the
various types of it. Iron homeostasis is a vital component in supporting biochemical …

Lipocalin 2: a new mechanoresponding gene regulating bone homeostasis

N Rucci, M Capulli, SG Piperni… - Journal of Bone and …, 2015 - academic.oup.com
Mechanical loading represents a crucial factor in the regulation of skeletal homeostasis. Its
reduction causes loss of bone mass, eventually leading to osteoporosis. In a previous global …

Gene expression profiling in peripheral blood cells and synovial membranes of patients with psoriatic arthritis

M Dolcino, A Ottria, A Barbieri, G Patuzzo, E Tinazzi… - PloS one, 2015 - journals.plos.org
Background Psoriatic arthritis (PsA) is an inflammatory arthritis whose pathogenesis is
poorly understood; it is characterized by bone erosions and new bone formation. The …