Vasa vasorum angiogenesis: key player in the initiation and progression of atherosclerosis and potential target for the treatment of cardiovascular disease

DG Sedding, EC Boyle, JAF Demandt… - Frontiers in …, 2018 - frontiersin.org
Plaque microvascularization and increased endothelial permeability are key players in the
development of atherosclerosis, from the initial stages of plaque formation to the occurrence …

The role of perivascular adipose tissue in obesity‐induced vascular dysfunction

N Xia, H Li - British journal of pharmacology, 2017 - Wiley Online Library
Under physiological conditions, perivascular adipose tissue (PVAT) attenuates agonist‐
induced vasoconstriction by releasing vasoactive molecules including hydrogen peroxide …

Vasa vasorum in normal and diseased arteries

MJ Mulligan-Kehoe, M Simons - Circulation, 2014 - Am Heart Assoc
2558 Circulation June 17, 2014 hierarchy in hypercholesterolemic low-density lipoprotein
receptor–deficient/apolipoprotein B100–only mice (LDLR−/− ApoB100/100) mice. 33 The …

Regional differences in perivascular adipose tissue impacting vascular homeostasis

M Gil-Ortega, B Somoza, Y Huang, M Gollasch… - Trends in Endocrinology …, 2015 - cell.com
Perivascular adipose tissue (PVAT) releases several important vasoactive factors with
physiological and pathophysiological paracrine effects. A large body of evidence suggests …

Does stenosis severity of native vessels influence bypass graft patency? A prospective fractional flow reserve–guided study

CJ Botman, J Schonberger, S Koolen, O Penn… - The Annals of thoracic …, 2007 - Elsevier
BACKGROUND: After coronary bypass surgery, occlusion or narrowing of bypass grafts may
occur over time. The present study prospectively evaluated the angiographic patency of …

[HTML][HTML] The “no-touch” harvesting technique for vein grafts in coronary artery bypass surgery preserves an intact vasa vasorum

M Dreifaldt, DSR Souza, A Loesch, JR Muddle… - The Journal of thoracic …, 2011 - Elsevier
OBJECTIVES: Our objective was to evaluate the impact of vein graft harvesting technique on
structure and function of vasa vasorum. METHODS: Paired segments of great saphenous …

Role of PVAT in coronary atherosclerosis and vein graft patency: friend or foe?

MS Fernández‐Alfonso, M Gil‐Ortega… - British journal of …, 2017 - Wiley Online Library
Perivascular adipose tissue (PVAT) releases numerous factors and adipokines with
paracrine effects on both vascular structure and function. These effects are variable as they …

Slower progression of atherosclerosis in vein grafts harvested with 'no touch'technique compared with conventional harvesting technique in coronary artery bypass …

BL Johansson, DSR Souza, L Bodin… - European journal of …, 2010 - academic.oup.com
Objectives: In a long-term randomised coronary artery bypass grafting (CABG) study, the
patency rate using a new 'no touch'(NT) vein-graft preparation technique was superior to the …

'No-touch'saphenous vein harvesting improves graft performance in patients undergoing coronary artery bypass surgery: a journey from bedside to bench

MR Dashwood, JC Tsui - Vascular Pharmacology, 2013 - Elsevier
The saphenous vein is the most commonly used conduit in patients undergoing coronary
artery bypass surgery yet its patency is inferior to the internal thoracic artery. Vascular …

Does periadventitial fat-derived nitric oxide play a role in improved saphenous vein graft patency in patients undergoing coronary artery bypass surgery?

MR Dashwood, A Dooley, X Shi-Wen… - Journal of vascular …, 2007 - karger.com
Background/Aims: The saphenous vein is commonly used for coronary artery bypass
surgery but its patency is poor. Vascular damage occurs during conventional surgery …