This paper describes the ability of a new class of heterocyclic γ‐amino acids named ATCs (4‐
amino (methyl)‐1, 3‐thiazole‐5‐carboxylic acids) to induce turns when included in a …

Antimicrobial peptides (AMPs) are considered as potential therapeutic sources of future
antibiotics because of their broad-spectrum activities and alternative mechanisms of action …

Unlike bacteria and viruses, which are based on DNA and RNA, prions are unique as
disease-causing agents since they are misfolded proteins. Prion diseases are called" …

The tendency of oligopeptides composed of g-amino acids to fold into helical structures was
first observed by the groups of Seebach and Hanessian in their studies of short g peptide …

Original αγα tripeptides containing one β, γ-diamino acid have been synthesized and their
conformation determined by extensive NMR and molecular dynamic studies. These studies …

Abstract 26S proteasome is an intracellular; ATP dependent enzymatic complex degrades
ubiquitin-tagged proteins and maintains cellular homeostasis. The orderly degraded …

We synthesized and carried out the conformational analysis of several hybrid dipeptides
consisting of an α‐amino acid attached to a quaternary glyco‐β‐amino acid. In particular, we …

The peptides vaccines are composed of the twenty genetically coded amino acids generally
exist as an ensemble of different conformational states in solution. The induction of folded …

The solution conformations of the αγ‐hybrid oligopeptides Boc–[Aib–γ4 (R) Val] n–OMe (n=
1–8) in organic solvents have been probed by NMR, IR, and CD spectroscopic methods. In …

The present study describes the solid‐state conformation of αβ hybrid peptides, Boc‐Leu‐
β3, 3‐Ac6c‐OH, P1; Boc‐Leu‐β3, 3‐Ac6c‐Leu‐β3, 3‐Ac6c‐OMe, P2; and Boc‐Leu‐β3, 3 …