Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements
M Sharma, PV Wyszkiewicz… - Physics in Medicine …, 2022 - iopscience.iop.org
Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …
Pulmonary functional MRI: Detecting the structure–function pathologies that drive asthma symptoms and quality of life
HK Kooner, MJ McIntosh, V Desaigoudar… - …, 2022 - Wiley Online Library
Pulmonary functional MRI (PfMRI) using inhaled hyperpolarized, radiation‐free gases (such
as 3He and 129Xe) provides a way to directly visualize inhaled gas distribution and …
as 3He and 129Xe) provides a way to directly visualize inhaled gas distribution and …
Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …
PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …
terminal airway morphology rapidly and safely, providing novel information not possible …
Effects of dupilumab on mucus plugging and ventilation defects in patients with moderate-to-severe asthma: a randomized, double-blind, placebo-controlled trial
S Svenningsen, M Kjarsgaard, E Haider… - American Journal of …, 2023 - atsjournals.org
Methods We completed a single-center, randomized, double-blind, placebo-controlled trial
(ClinicalTrials. gov identifier NCT 03884842) in 25 adults with uncontrolled moderate to …
(ClinicalTrials. gov identifier NCT 03884842) in 25 adults with uncontrolled moderate to …
Postacute COVID-19 Syndrome: 129Xe MRI Ventilation Defects and Respiratory Outcomes 1 Year Later
Background In individuals with postacute COVID-19 syndrome (PACS) and normal
pulmonary function, xenon 129 (129Xe) MRI ventilation defects, abnormal quality-of-life …
pulmonary function, xenon 129 (129Xe) MRI ventilation defects, abnormal quality-of-life …
Heterogeneity of airway smooth muscle remodeling in asthma
AL James, GM Donovan, FHY Green… - American journal of …, 2023 - atsjournals.org
Rationale: Ventilatory defects in asthma are heterogeneous and may represent the
distribution of airway smooth muscle (ASM) remodeling. Objectives: To determine the …
distribution of airway smooth muscle (ASM) remodeling. Objectives: To determine the …
Functional imaging for assessing regional lung ventilation in preclinical and clinical research
D Karmali, M Sowho, S Bose, J Pearce… - Frontiers in …, 2023 - frontiersin.org
Dynamic heterogeneity in lung ventilation is an important measure of pulmonary function
and may be characteristic of early pulmonary disease. While standard indices like …
and may be characteristic of early pulmonary disease. While standard indices like …
Functional lung avoidance for individualized radiation therapy: Results of a double-masked, randomized controlled trial
Purpose To determine whether functional lung avoidance based on 3 He magnetic
resonance imaging (MRI) improves quality of life (QOL) for patients undergoing concurrent …
resonance imaging (MRI) improves quality of life (QOL) for patients undergoing concurrent …
Same‐day repeatability and 28‐day reproducibility of Xenon MRI ventilation in children with cystic fibrosis in a multi‐site trial
LL Walkup, DJ Roach, JW Plummer… - Journal of Magnetic …, 2024 - Wiley Online Library
Background MRI with xenon‐129 gas (Xe MRI) can assess airflow obstruction and
heterogeneity in lung diseases. Specifically, Xe MRI may represent a sensitive modality for …
heterogeneity in lung diseases. Specifically, Xe MRI may represent a sensitive modality for …
Human upper-airway respiratory airflow: In vivo comparison of computational fluid dynamics simulations and hyperpolarized 129Xe phase contrast MRI velocimetry
Computational fluid dynamics (CFD) simulations of respiratory airflow have the potential to
change the clinical assessment of regional airway function in health and disease, in …
change the clinical assessment of regional airway function in health and disease, in …