L-Glutamic acid is the main excitatory neurotransmitter in the central nervous system (CNS).
Its associated receptors localized on neuronal and non-neuronal cells mediate rapid …

Delirium is a common, morbid, and costly syndrome that is closely linked to Alzheimer's
disease (AD) and AD‐related dementias (ADRD) as a risk factor and outcome. Human …

Background Alzheimer's disease (AD) is a prevalent neurodegenerative disorder causing
progressive dementia. Research suggests that microRNAs (miRNAs) could serve as …

Direct nose-to-brain drug delivery offers the opportunity to treat central nervous system
disorders more effectively due to the possibility of drug molecules reaching the brain without …

Alzheimer's disease (AD) is a devastating neurodegenerative disease with limited
therapeutic options. Cellular transplantation of healthy exogenic neurons to replace and …

A form of dementia distinct from healthy cognitive aging, Alzheimer's disease (AD) is a
complex multi-stage disease that currently afflicts over 50 million people worldwide …

The synthetic approaches to three new AMPA receptor modulators—derivatives of 1, 11-
dimethyl-3, 6, 9-triazatricyclo [7.3. 1.13, 11] tetradecane-4, 8, 12-trione—had been …

Parkinson's disease (PD) is a highly heterogeneous and therefore a possible cause of
translation failure of drugs from animal testing to human treatments can be because existing …

Neurodegenerative diseases (NDs) are severe disorders of the nervous system, and their
causes are still not completely understood. Modeling the complex pathological mechanisms …

Neurological disorders, encompassing conditions such as Alzheimer's disease (AD),
Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis …